Results 51 to 60 of about 1,019,538 (305)

Maternal Expression Relaxes Constraint on Innovation of the Anterior Determinant, bicoid [PDF]

, 2005
The origin of evolutionary novelty is believed to involve both positive selection and relaxed developmental constraint. In flies, the redesign of anterior patterning during embryogenesis is a major developmental innovation and the rapidly evolving Hox ...
David Stern, Jeffery P Demuth, Michael J Wade, Michael S Barker   +3 more
core   +4 more sources

Maternal nutritional status mediates the association between maternal age and birth outcomes [PDF]

, 2020
Young maternal age during pregnancy is linked with adverse birth outcomes. This study examined the role of maternal nutritional status in the association between maternal age and small for gestational age (SGA) delivery and birth length.
Argaw, Alemayehu, Belachew, Tefera, Bushra, Abdulhalik Workicho, Ghosh, Shibani, Kershaw, Meghan, Kolsteren, Patrick, Lachat, Carl, Roba, Alemzewed   +7 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Agrestal Environments and Maternal Genetic Effects Weaken the Ecological Barriers for Crop to Wild Introgression in Sunflower

Ecology and Evolution
Admixture between crops and their wild relatives may lead to the evolution of aggressive weeds in agricultural and natural habitat. As many crops and their wild relatives belong to the same species, admixture is common, and the low fitness of crop‐wild ...
Ignacio J. Fanna, Fernando Hernández, Kristin L. Mercer, Alejandro Presotto   +3 more
doaj   +1 more source

PENGUJIAN PENGARUH TETUA BETINA TERHADAP SIFAT TOLERANSI PADA NAUNGAN KEDELAI [Glycine max (L.) Merill]

Caraka Tani: Journal of Sustainable Agriculture, 2008
This study was conducted at Green House IPB Cikabbayan Darmaga Research Station. Soybean tolerance genotype (Ceneng) was crossed with sensitive genotype (Godek A) to study the mode of inheritance in tolerance to shade.
Titin Handayani
doaj   +1 more source

Estimation of (Co) Variance Components and Genetic Parameters for Pre- and Post-Weaning Growth Traits in Dağlıç Sheep

Animals, 2023
The goal of this study was to estimate (co) variance components and genetic parameters for pre- and post-weaning growth traits in Dağlıç sheep, considering the direct additive genetic, maternal genetic, and maternal permanent environmental effects, with ...
Serdar Koçak, Samet Çinkaya, Mustafa Tekerli, Mustafa Demirtaş, Zehra Bozkurt, Koray Çelikeloğlu, Özlem Hacan, Metin Erdoğan   +7 more
doaj   +1 more source

A mediation approach to understanding socio-economic inequalities in maternal health-seeking behaviours in Egypt. [PDF]

, 2015
BACKGROUND: The levels and origins of socio-economic inequalities in health-seeking behaviours in Egypt are poorly understood. This paper assesses the levels of health-seeking behaviours related to maternal care (antenatal care [ANC] and facility ...
A Singh-Manoux, A Skrondal, AJD Barros, AM Basu, B Galobardes, C Marston, CG Victora, CK Stanton, D Filmer, D McKenzie, DJ Bartholomew, DJ Corsi, DM Hafeman, F El-Zanaty, F Tabassum, George B Ploubidis, H Gowayed, J Cleland, J Falkingham, JN Hobcraft, JT Boerma, KH Nada, L Ashford, L Benova, L Howe, L Liu, Lenka Benova, M Lidelow, NE Adler, O Campbell, O Campbell, Oona MR Campbell, R Gipson, R Hicks, S Ahmed, S Devi, S Gabrysch, S Rutstein, T Kabakian-Khasholian, T Stowasser, TA Houweling, The World Bank, TP Eisele, TR Have Ten, World Health Organization, World Health Organization   +45 more
core   +2 more sources

Multigenerational Effects of Maternal Undernutrition [PDF]

Cell Metabolism, 2014
Intrauterine exposure to reduced nutrient availability can have major effects in determining susceptibility to chronic disease later in life. Martínez et al. (2014) demonstrate multigenerational effects of poor maternal nutrition and evidence of germline transmission through alterations in DNA methylation.
openaire   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source