Results 91 to 100 of about 796,901 (357)

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Immigration and Adverse Pregnancy Outcomes in an Italian Free Care Hospital

International Journal of Women's Health, 2021
Giuseppe Caruso,1 Eleonora Marcoccia,1,2 Roberto Brunelli,1 Miriam Candelieri,1 Michele Carlo Schiavi,1 Ilaria Zannini,1 Seila Perrone,1 Oriana Capri,1 Ludovico Muzii,1 Giuseppina Perrone,1 Paola Galoppi1 1Department of Maternal and Child Health and ...
Caruso G, Marcoccia E, Brunelli R, Candelieri M, Schiavi MC, Zannini I, Perrone S, Capri O, Muzii L, Perrone G, Galoppi P   +10 more
doaj  

Ultrasonographic Evaluation of Uterine LSCS Scar and its Impact on Maternal Outcomes: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The evaluation of uterine scars following Caesarean Section (CS) is essential for predicting delivery outcomes, particularly in patients considering Vaginal Birth After Caesarean (VBAC) or those undergoing repeat Lower Segment Caesarean ...
Hemant Deshpande, Rohit Dimbar, Shriraj Katakdhond, Saba Chaudhary   +3 more
doaj   +1 more source

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes

Advanced Science, EarlyView.
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian, Jiatong Li, Jingyi Kang, Xiangning Xu, Bicheng Wang, Shuo Lou, Jingyu Li, Yuying Yang, Yanbing Zhang, Yangzi Zheng, Jing Weng, Yuanjing Liang, Wei Ma   +12 more
wiley   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Effect of Implementing Enhanced Recovery After Surgery Pathway for Women Undergoing Cesarean Section on Maternal Outcomes and Satisfaction [PDF]

, 2023
Isis Emile Gohar, Heba Saied Ibrahim Ali, Neama Saad Mahmoud Shoukhba   +2 more
openalex   +1 more source

Intrafamily Resource Allocations: A Dynamic Model of Birth Weight [PDF]

This paper estimates a model of dynamic intrahousehold investment behavior which incorporates family fixed effects and child endowment heterogeneity. This framework is applied to large American and British survey data on birth outcomes, with focus on the
Del Bono, Emilia, Ermisch, John, Francesconi, Marco   +2 more
core  

Poverty, Maternal Depression, Family Status and Children's Cognitive and Behavioural Development in Early Childhood: A Longitudinal Study [PDF]

, 2009
Improving children's lives is high on the UK policy agenda. In this study for a recent birth cohort of UK children we examine how three aspects of parental resources - income, mother's mental well-being and family status - in early childhood enhance or ...
Kiernan, Kathleen E., Mensah, Fiona K.
core   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Maternal Multiple Sclerosis and Health Outcomes Among the Children: A Systematic Review

, 2023
Mette Louise Andersen, Line Riis Jølving, Egon Stenager, Torben Knudsen, Bente Mertz Nørgård   +4 more
openalex   +2 more sources