Results 121 to 130 of about 2,028,316 (397)

Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala

Frontiers in Neuroscience, 2019
Converging evidence suggests a role of serotonin (5-hydroxytryptamine, 5-HT) and tryptophan hydroxylase 2 (TPH2), the rate-limiting enzyme of 5-HT synthesis in the brain, in modulating long-term, neurobiological effects of early-life adversity.
Magdalena T. Weidner, Magdalena T. Weidner, Magdalena T. Weidner, Roy Lardenoije, Roy Lardenoije, Roy Lardenoije, Lars Eijssen, Lars Eijssen, Floriana Mogavero, Lilian P. M. T. De Groodt, Sandy Popp, Rupert Palme, Konrad U. Förstner, Konrad U. Förstner, Konrad U. Förstner, Tatyana Strekalova, Tatyana Strekalova, Tatyana Strekalova, Harry W. M. Steinbusch, Angelika G. Schmitt-Böhrer, Jeffrey C. Glennon, Jonas Waider, Daniel L. A. van den Hove, Daniel L. A. van den Hove, Klaus-Peter Lesch, Klaus-Peter Lesch, Klaus-Peter Lesch   +26 more
doaj   +1 more source

Early maternal separation: Neurobehavioral consequences in mother rats

Behavioural Brain Research, 2013
Repeated separation of dams from their pups during the postpartum period may evoke emotional stress in the dam. In the present study we investigated whether prolonged maternal separation is stressful for rat dams by studying different behavioral and central responses known to be affected by stress.
Aguggia, Julieta Paola, Suarez, Marta Magdalena, Rivarola, María Angélica   +2 more
openaire   +3 more sources

Short environmental enrichment in adulthood reverses anxiety and basolateral amygdala hypertrophy induced by maternal separation

Translational Psychiatry, 2016
Maternal separation during early childhood results in greater sensitivity to stressors later in adult life. This is reflected as greater propensity to develop stress-related disorders in humans and animal models, including anxiety and depression ...
Amelia S. Koe, A. Ashokan, R. Mitra
semanticscholar   +1 more source

Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length

Advanced Science, EarlyView.
Different from mitosis, the female meiosis undergoes asymmetric division that produces haploid oocytes and polar body, which is essential for retaining maternal components to support subsequent fertilization and embryo development. However, the underlying mechanisms are still largely unknown.
Yu Li, Hanwen Zhang, Wenjun Zeng, Yilong Miao, Shaochen Sun, Yu Zhang, Bo Xiong   +6 more
wiley   +1 more source

FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single‐Cell RNA‐Seq Samples

Advanced Science, EarlyView.
FemXpress is a computational tool that leverages X‐linked single nucleotide polymorphisms (SNPs) to group cells by the origin of the inactivated X chromosome in female single‐cell RNA sequencing (scRNA‐Seq) data. It demonstrates strong performance on both simulated and real datasets without requiring parental genomic information, and can also identify ...
Xin Wang, Yingke Ma, Fan Li, Wentao Cui, Tianshi Pan, Siqi Wang, Sinan Ma, Qingtong Shan, Chao Liu, Yukai Wang, Ying Zhang, Yuanchun Zhou, Wei Li, Pengfei Wang, Qi Zhou, Guihai Feng   +15 more
wiley   +1 more source

Fabrication and testing of microfluidic devices for blood cell separation [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Desmulliez, MPY, Dhariwal, RS, Kavanagh, DM, Kersaudy-Kerhoas, M, Pavuluri, SK   +5 more
core  

Influence of morning maternal care on the behavioural responses of 8-week-old Beagle puppies to new environmental and social stimuli [PDF]

, 2016
In mammals, maternal care represents a major constituent of the early-life environment and its influence on individual development has been documented in rodents, non-human primates, humans and recently in adult dogs.
Bowen, J, Fatjò, J, Gazzano, A, Guardini, G, Mariti, C, Martorell, A, Ruzzante, S, Sighieri, C   +7 more
core   +1 more source

DNA Sequential Logic Circuits for Reversible Counters and Dynamic Biomolecular Sensing

Advanced Science, EarlyView.
In this work, a DNA sequential logic circuit is constructed that combines reusability and autonomy for the first time, including SR (Set‐Reset)‐latches composed of NOR gates, SR‐latches composed of NAND gates, and D (Data)‐latches. After fully utilizing the characteristics of each latch, to counter, toxin and miRNA detection and intracellular dynamic ...
Tianci Xie, Changjiang Li, Minghao Hu, Xingyu Zhong, Junbin Xiao, Zhen Zhang, Ze Wang, Tongbo Wu   +7 more
wiley   +1 more source

Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat [PDF]

, 2002
Earlier studies at our laboratory indicated that several hydroxylated polychlorinated biphenyls (OH-PCBs) detected in human blood could specifically inhibit thyroxine (T4) transport by competitive binding to the thyroid hormone transport protein ...
Assink, Y., Berg, J.H.J. van den, Bergman, A., Brouwer, A., Cenijn, P.H., Koeman, J.H., Meerts, I.A.T.M., Weijers, B.M.   +7 more
core   +4 more sources

Maternal separation affects expression of stress response genes and increases vulnerability to ethanol consumption

Brain and Behavior, 2017
Maternal separation is an early life stress event associated with behavioral alterations and ethanol consumption. We aimed to expand the current understanding on the molecular mechanisms mediating the impact of postnatal stress on ethanol consumption.
Taciani de Almeida Magalhães, D. Correia, L. M. de Carvalho, Samara Damasceno, A. L. Brunialti Godard   +4 more
semanticscholar   +1 more source