Results 251 to 260 of about 2,028,316 (397)

Maternal separation increases alcohol-drinking behaviour and reduces endocannabinoid levels in the mouse striatum and prefrontal cortex [PDF]

, 2018
Marta Portero Tresserra, Irene Gracia‐Rubio, Lídia Cantacorps, Óscar J. Pozo, Àlex Gomez‐Gómez, Antoni Pastor, Raúl López‐Arnau, Rafael de la Torre, Olga Valverde   +8 more
openalex   +1 more source

Cocaine-Induced Impulsivity is Differentially Expressed in Male and Female Mice Exposed to Maternal Separation and is Associated with Alterations in AMPA Receptors Subunits [PDF]

, 2020
Adriana Castro‐Zavala, Ana Martín‐Sánchez, Larisa Montalvo-Martínez, Alberto Camacho‐Morales, Olga Valverde   +4 more
openalex   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Cognitive impairment following maternal separation in rats mediated by the NAD⁺/SIRT3 axis via modulation of hippocampal synaptic plasticity. [PDF]

Transl Psychiatry
Hao K, Chen F, Xu S, Xiong Y, Xu R, Huang H, Shu C, Lv Y, Wang G, Wang H.   +9 more
europepmc   +1 more source

Maternal separation leads to dynamic changes of visceral hypersensitivity and fecal metabolomics from childhood to adulthood. [PDF]

Sci Rep, 2023
Chen X, Hu C, Yan C, Tao E, Zhu Z, Shu X, Guo R, Jiang M.   +7 more
europepmc   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

One-Week Maternal Separation Caused Sex-Specific Changes in Behavior and Hippocampal Metabolomics of Offspring Rats. [PDF]

Brain Sci
Dong MC, Chen YX, Sun XR, Jiang N, Chang Q, Liu XM, Pan RL.   +6 more
europepmc   +1 more source

The mineralocorticoid receptor and extra-synaptic NMDA receptor in the lateral habenula involve in the vulnerability to early life stress in the maternal separation model. [PDF]

Neurobiol Stress, 2023
Kang M, Chung JM, Noh J, Kim J.
europepmc   +1 more source

Maternal Separation during Breastfeeding Induces Gender-Dependent Changes in Anxiety and the GABA-A Receptor Alpha-Subunit in Adult Wistar Rats

, 2013
Diego Armando León Rodríguez, Zulma Dueñas   +1 more
openalex   +2 more sources

Moderate maternal separation mitigates the altered synaptic transmission and neuronal activation in amygdala by chronic stress in adult mice [PDF]

, 2019
Xia Qin, Ye He, Na Wang, Jia‐Xin Zou, Yong-Mei Zhang, Jun‐Li Cao, Bing‐Xing Pan, Wen‐Hua Zhang   +7 more
openalex   +1 more source