Results 41 to 50 of about 239,639 (261)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Increasing Mathematical Literacy and Numeracy Abilities with Problem-Based Learning Model Through Technological Pedagogical Content Knowledge

Hexagon
The background of this research was that nowadays high school students are required to have a significant understanding and appreciation of mathematics.
Masta Hutajulu, Eva Dwi Minarti
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The Nature of Math Anxiety in Adults: Prevalence and Correlates

Journal of Numerical Cognition, 2019
It is important to understand the nature of math anxiety in the general adult population, as the importance of math skills does not end when one leaves school. To this end, we present a well-powered, preregistered study of English-speaking U.S.
Sara Ann Hart, Colleen Marie Ganley
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Learning Assistance For Blind Students to Improve Mathematical Ability

The Spirit of Society Journal: International Journal of Society Development and Engagement, 2022
In Indonesia, an education system is implemented where students with special learning needs can get an education in public schools. One type of child with special needs accepted by public schools is blind.
Dian Permatasari
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Cognitive diagnosis and algorithmic cultural analysis of fourth-grade Yi students’ mathematical skills in China: A case study of several primary schools in Puge county, Liangshan prefecture

Frontiers in Psychology, 2023
The Liangshan Yi Autonomous Prefecture is the largest area in China inhabited by the Yi people, and the original Yi characteristics and culture are well maintained.
Hong Zhang, Shuang Ye, Lingke Shi
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

DESKRIPSI KEMAMPUAN LITERASI MATEMATIS SISWA MADRASAH TSANAWIYAH NEGERI DI KOTA KENDARI

Al-Izzah, 2019
Mathematical literacy is the ability to understand and use mathematics in various contexts to solve problems and be able to explain to others how to use mathematics. This study aims to describe the mathematical literacy skills of MTsN students in Kendari
Tandri - Patih
doaj   +1 more source