Results 111 to 120 of about 1,696,822 (255)

The one‐dimensional cutting stock problem with sequence‐dependent setups

International Transactions in Operational Research, EarlyView.
Abstract The cutting stock problem (CSP) is a classic operations research problem with several applications in real‐world scenarios. It involves cutting large objects into smaller items to satisfy customer demands, minimizing the number of cut objects.
Eduardo M. Silva, Antônio A. Chaves, Mauricio G. C. Resende, Silvio A. de Araujo   +3 more
wiley   +1 more source

A design principle for neuronal firing with up-down oscillation through Na+ dynamics

iScience
Summary: Nonrapid eye movement sleep is characterized by high-amplitude and low-frequency electroencephalography signals. These signals are thought to be produced by the synchronized activity of cortical neurons, demonstrating the alternating bursting ...
Tomohide R. Sato, Koji L. Ode, Fukuaki L. Kinoshita, Hiroki R. Ueda   +3 more
doaj   +1 more source

When biology meets materials science – Interdisciplinary applications of electron microscopy

Journal of Microscopy, EarlyView.
Abstract Research at the interface between biology and materials science creates challenges for electron microscopists. Everything from the sample preparation to the choice of imaging and analytical techniques and the interpretation of the resulting data refuses to sit comfortably within the domain of one discipline or the other.
Martin Saunders, Peta L. Clode, Enoch V. S. Wong, Anna‐Lee Jessop, Gerd E. Shröder‐Turk, Felix de Tombeur   +5 more
wiley   +1 more source

Evolutionary shifts to gynomonoecy correlate with changes in capitulum architecture in South African Helichrysum (Asteraceae)

New Phytologist, EarlyView.
Representative South African Helichrysum species illustrating variation in capitulum size. Summary Gynomonoecy has evolved repeatedly in Asteraceae, suggesting selective advantages for species whose capitula combine pistillate and bisexual flowers. Theories invoking conspicuous peripheral flowers and achene heteromorphism do not account for gynomonoecy
Zaynab Shaik, Nicola G. Bergh, Carme Blanco‐Gavaldà, G. Anthony Verboom   +3 more
wiley   +1 more source

Structural Variations Contribute to Subspeciation and Yield Heterosis in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Yield heterosis has been extensively exploited in hybrid breeding, with intersubspecific hybrids often exhibiting the most pronounced effects. However, developing elite hybrids remains a laborious and time‐consuming process. The genetic basis of heterosis has been debated for over a century, hindered largely by the lack of high‐quality genomes.
Zhiwu Dan, Yunping Chen, Wenchao Huang
wiley   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida, Nadja Koechli, Edgar Ontsouka, Chennakesava Cuddapah, Martin Mueller, Bram Sengers, Frantisek Staud, Christiane Albrecht   +7 more
wiley   +1 more source

Model selection reveals selective regulation of blood amino acid and lipid metabolism by insulin in humans

iScience
Summary: Insulin plays a crucial role in regulating the metabolism of blood glucose, amino acids (aa), and lipids in humans. However, the mechanisms by which insulin selectively regulates these metabolites are not fully understood.
Suguru Fujita, Ken-ichi Hironaka, Yasuaki Karasawa, Shinya Kuroda   +3 more
doaj   +1 more source

Mathematical Modelling in Biosciences and Discrete Optimization [PDF]

This thesis explores innovative methodologies in two distinct areas of Applied Mathematics: Mathematical Modelling in Biosciences and Discrete Optimization.
Milanesi, Simone
core  

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source