Results 91 to 100 of about 1,696,822 (255)

Dynamic Emergence of Observed and Hidden Intra-tumor Heterogeneity

open access: yesiScience, 2019
Summary: Intra-tumor heterogeneity is frequently observed in cancer patients, and it is associated with therapeutic resistance and disease relapse. However, its systematic assessment is still limited and often unfeasible.
Franck Raynaud   +2 more
doaj   +1 more source

Dynamics of biosciences regulation and opportunities for biosciences innovation in Africa: Exploring regulatory policy brokering [PDF]

open access: yes
Knowledge brokering has been explored in the innovation literature to understand how different innovation tasks are organised toward technological development.
Hall, Andy, Kingiri, Ann
core  

Ground‐based robotic remote sensing for standardized biodiversity monitoring in coastal habitats

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Illustrated workflow of the proposed citizen‐to‐robot monitoring pipeline: (i) expert‐validated citizen observations are translated into AI models, (ii) deployed on a ground‐based robotic platform for proximal sensing of coastal dune habitats, (iii) enabling standardized detection of ecological targets (e.g., Pancratium maritimum & Brithys crini), and (
Giovanni Di Lorenzo   +5 more
wiley   +1 more source

Coupling of DNA Replication and Negative Feedback Controls Gene Expression for Cell-Fate Decisions

open access: yesiScience, 2018
Summary: Cellular decision-making arises from the expression of genes along a regulatory cascade, which leads to a choice between distinct phenotypic states. DNA dosage variations, often introduced by replication, can significantly affect gene expression
Qiuyan Shao   +5 more
doaj   +1 more source

Reply to determining structural identifiability of parameter learning machines [PDF]

open access: yes, 2016
The paper Ran and Hu (2014, Neurocomputing) examines identifiability and parameter redundancy in classes of models used in machine learning. This note discusses the results on global identifiability and also clarifies that the paper's results on ...
Cole, Diana J.
core   +1 more source

Context‐Dependent Radioenhancement by Platinum Nanoparticles Under Conventional and Ultra‐High Dose‐Rate “FLASH” Radiotherapy

open access: yesSmall, EarlyView.
Overview of the experimental workflow and main findings of the study investigating Pt‐NPs‐mediated radioenhancement under conventional 134 dose‐rate (CONV) and ultrahigh dose‐rate (UHDR) 9 MeV electron irradiation. Pt‐NP distribution and uptake were characterized in 4T1 spheroids and syngeneic tumor models.
Cathyanne Schott   +14 more
wiley   +1 more source

Bifurcation study of blood flow control in the kidney.

open access: yes, 2015
Renal blood flow is maintained within a narrow window by a set of intrinsic autoregulatory mechanisms. Here, a mathematical model of renal hemodynamics control in the rat kidney is used to understand the interactions between two major renal ...
Makrides, Elizabeth   +4 more
core   +1 more source

Resolving Real‐Time Interfacial Dynamics on Garnet‐Based Solid‐State Electrolytes via Snapshot Operando XPS

open access: yesSmall Methods, EarlyView.
This work establishes snapshot operando x‐ray photoelectron spectroscopy (XPS) as a compelling laboratory‐based technique for real‐time probing of dynamic interfaces in solid‐state batteries. By combining second‐scale temporal resolution with complementary HAXPES depth profiling, the methodology enables direct observation of electrochemical processes ...
Arda Baran Burçak   +6 more
wiley   +1 more source

Virginia Bioinformatics Institute announces partnership with Mathematical Biosciences Institute

open access: yes, 2008
The Virginia Bioinformatics Institute (VBI) at Virginia Tech has established a new partnership with the Mathematical Biosciences Institute (MBI)
Bland, Susan
core  

Mechanistic scaling of twig allometry and crown architecture in Scots pine: implications for moose browse availability

open access: yesWildlife Biology, EarlyView.
Balancing moose Alces alces populations with forest production objectives remains a major challenge in Swedish forestry. We developed a mechanistic, data‐driven model of browse availability in Scots pine Pinus sylvestris saplings by linking shoot‐level allometry, crown architecture, and tree height development.
Christer Kalén   +2 more
wiley   +1 more source

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