Results 81 to 90 of about 72,487 (242)

Beyond PBMCs: Polymer‐Based Cell Mimics for Robust TBNK Immunophenotyping Assay Validation

Cytometry Part A, EarlyView.
ABSTRACT Flow cytometry‐based TBNK immunophenotyping is widely used to assess immune status in research, clinical diagnostics, and cell therapy development. Biological control materials such as PBMCs often serve as physiologically relevant controls, but suffer from considerable variability due to donor differences, limited stability, and fluctuations ...
Swetha Pratyusha Gunturu, Subhanip Biswas, Armando Martinez, Brian Kerfs, Kanwal Palla, Louisa D'Lima   +5 more
wiley   +1 more source

Epidemics on Networks: Reducing Disease Transmission Using Health Emergency Declarations and Peer Communication

, 2019
Understanding individual decisions in a world where communications and information move instantly via cell phones and the internet, contributes to the development and implementation of policies aimed at stopping or ameliorating the spread of diseases. In
Azizi, Asma, Castillo-Chavez, Carlos, Espinoza, Baltazar, Kang, Yun, Montalvo, Cesar   +4 more
core   +1 more source

The effect of trait choice on hybrid species distribution model projections under climate change

Ecography, EarlyView.
Species distribution models (SDMs) have been increasingly combined with thermal performance data to enhance their transferability and to provide a physiological explanation for the predicted geographic patterns. Yet, while it is widely acknowledged that thermal sensitivities may vary among biological traits, it remains largely unexplored to what extent
Soria Delva, Jorge Assis, Kenny A. Bogaert, Aisling J. Daly, Wissam Barhdadi, Jan M. Baetens, Bernard De Baets, Olivier De Clerck   +7 more
wiley   +1 more source

Theoretical Study of Pest Control Using Stage Structured Natural Enemies with Maturation Delay: A Crop-Pest-Natural Enemy Model [PDF]

, 2013
In the natural world, there are many insect species whose individual members have a life history that takes them through two stages, immature and mature. Moreover, the rates of survival, development, and reproduction almost always depend on age, size, or
Dhar, Joydip, Jatav, Kunwer Singh
core  

Patterns of seizure frequency reduction in clinical trial participants with lower baseline seizure frequency

Epilepsia, EarlyView.
Abstract Objective Inclusion and exclusion criteria of clinical trials for seizures aim to select representative participants with a high enough seizure frequency to evaluate the efficacy of treatment in a relatively short double‐blind period. To inform the selection of seizure frequency‐based inclusion criteria, we evaluated the association between ...
Wesley T. Kerr, Advith S. Reddy, Neo Kok, Katherine N. McFarlane, Lavanya Biju, Jacqueline A. French   +5 more
wiley   +1 more source

Development of a step‐gradient simulated moving bed process for the polishing of monoclonal antibodies with anion exchange chromatography

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND In recent years, biopharmaceutical applications in medicine have seen explosive growth and the need for efficient, rapid and inexpensive purification of these targets is the topic of tremendous research and development. The need to improve process efficiency has been an active area of investigation due to the tremendous potential ...
Yasmina MJ Harsy, Jonas Wege, Anthony Grabski, Romain Dabre, Egbert Müller, Carsten‐René Arlt   +5 more
wiley   +1 more source

Algebraic moment closure for population dynamics on discrete structures

, 2014
Moment closure on general discrete structures often requires one of the following: (i) an absence of short closed loops (zero clustering); (ii) existence of a spatial scale; (iii) ad hoc assumptions.
House, Thomas
core   +1 more source

A Brainstem Radiomics Framework to Distinguish Progressive Supranuclear Palsy from Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Differentiating progressive supranuclear palsy (PSP) from Parkinson's disease (PD) can be clinically challenging. In the neuroimaging field, radiomics has emerged as a promising approach to capture subtle microstructural and textural image alterations, improving differential diagnoses.
Chiara Camastra, Jolanda Buonocore, Antonio Augimeri, Camilla Calomino, Maria Giovanna Bianco, Alessia Sarica, Pier Paolo Arcuri, Aldo Quattrone, Andrea Quattrone   +8 more
wiley   +1 more source

Cell-state transitions and density-dependent interactions together explain the dynamics of spontaneous epithelial-mesenchymal heterogeneity

iScience
Summary: Cancer cell populations comprise phenotypes distributed among the epithelial-mesenchymal (E-M) spectrum. However, it remains unclear which population-level processes give rise to the observed experimental distribution and dynamical changes in E ...
Paras Jain, Ramanarayanan Kizhuttil, Madhav B. Nair, Sugandha Bhatia, Erik W. Thompson, Jason T. George, Mohit Kumar Jolly   +6 more
doaj   +1 more source

Quantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...
James A. Bankson, Joshua S. Niedzielski, Collin J. Harlan, Yunyun Chen, Christopher M. Walker, Philip L. Lorenzi, Lin Tan, Vikas Kundra, Matthew E. Merritt, Mukundan Ragavan, Dawid Schellingerhout, Renjie He, Yao Ding, Sahana Datar, Qing Wang, Christine B. Peterson, Clifton D. Fuller, Vlad C. Sandulache, Stephen Y. Lai   +18 more
wiley   +1 more source