Results 71 to 80 of about 72,487 (242)

Mathematical models of avascular cancer [PDF]

open access: yes, 2005
This review will outline a number of illustrative mathematical models describing the growth of avascular tumours. The aim of the review is to provide a relatively comprehensive list of existing models in this area and discuss several representative ...
Chapman, S. J., Maini, P. K., Roose, T.
core  

How round is a protein? Exploring protein structures for globularity using conformal mapping. [PDF]

open access: yes, 2014
We present a new algorithm that automatically computes a measure of the geometric difference between the surface of a protein and a round sphere. The algorithm takes as input two triangulated genus zero surfaces representing the protein and the round ...
Hass, Joel, Koehl, Patrice
core   +2 more sources

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan   +4 more
wiley   +1 more source

The mechanics of Arabidopsis seed germination [PDF]

open access: yes, 2007
Germination is defined as the protrusion of the embryonic radicle through the seed coat layers (endosperm and testa). As the radicle elongates, the testa ruptures, followed by rupture of the endosperm.
Holdsworth, Michael   +3 more
core  

Minimum error correction-based haplotype assembly: considerations for long read data

open access: yes, 2020
The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites on each haploid chromosome.
de Ridder, Dick   +2 more
core   +1 more source

Introducing Experimental Design Concepts Improves Biochemistry Undergraduates' Experimental Laboratory Competence and Confidence

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Laboratory science education can provide a training ground for developing experimental design capabilities, the ability to critically assess a range of laboratory methods, and confidence in selecting, adapting, and performing laboratory techniques.
Nathan D. Tivendale   +2 more
wiley   +1 more source

Enhancing Knowledge and Technology Transfer: Determinants and Indicators of Successful University–Industry Collaboration

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Both universities and companies create value and innovation to maintain their position and remain competitive. Different, but still similar, with two goals that are shared. With their collaboration, they can enhance their pursuit of sustainability and as well corporate social responsibility by creating and delivering value and thus ...
Jana Hojnik   +4 more
wiley   +1 more source

Tissue-Specific Chk1 Activation Determines Apoptosis by Regulating the Balance of p53 and p21

open access: yesiScience, 2019
Summary: The DNA damage response (DDR) protects cells against genomic instability. Surprisingly, little is known about the differences in DDR across tissues, which may affect cancer evolutionary trajectories and chemotherapy response.
Marijn T.M. van Jaarsveld   +3 more
doaj   +1 more source

Determining Structurally Identifiable Parameter Combinations Using Subset Profiling [PDF]

open access: yes, 2013
Identifiability is a necessary condition for successful parameter estimation of dynamic system models. A major component of identifiability analysis is determining the identifiable parameter combinations, the functional forms for the dependencies between
Eisenberg, Marisa C.   +1 more
core  

Optimizing Cell Sorting Performance: A Comparative Study Utilizing Spectral Flow Cytometry

open access: yesCytometry Part A, EarlyView.
Strategy for the Evaluation of Multi‐way Sort Performance. ABSTRACT The introduction of full spectral technology in flow cytometry has facilitated access to an increasing number of markers to define cell subsets with higher precision. Cell sorting has a unique advantage to combine high throughput single cell analysis and recovery of rare live single ...
Jarina Pena DaMata   +2 more
wiley   +1 more source

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