Results 121 to 130 of about 1,696,822 (255)
ABSTRACT Most Mendelian randomization (MR) of dietary intake use the full set of genome‐wide significant (GWS) variants in the instrumental variable (IV), likely biasing causal estimates due to pleiotropy. To characterize the common methods to handle pleiotropy in dietary intake MR, we conducted a scoping review of the literature on dietary intake MR ...
Kristen J. Sutton +7 more
wiley +1 more source
Abstract Society generally presents sex inaccurately as a binary variable based on one or few trait(s), causing myriad issues, including the pursuit of reductionist biology experiments, the creation of laws that limit the rights of women, people with queer genders, and intersex folks, and greater student endorsement of gender stereotypes in ...
Emily P. Driessen +4 more
wiley +1 more source
Summary: This communication presents a mathematical mechanism-based model of the regenerating liver after drug-induced pericentral lobule damage resolving tissue microarchitecture.
Jieling Zhao +5 more
doaj +1 more source
PlantCV v4: Image analysis software for high‐throughput plant phenotyping
Abstract PlantCV is an open‐source Python project aimed at developing tools to address a range of image‐based, plant phenotyping questions. PlantCV has been used for more than 10 years to automate trait collection from image data, and the newest release, PlantCV version 4, continues to lower the barrier to entry for users without substantial coding ...
Haley Schuhl +61 more
wiley +1 more source
Abstract Lodging in sorghum (Sorghum bicolor (L.) Moench) presents a significant challenge for plant breeders due to the trade‐off between lodging resistance and grain yield. Manually measuring lodging across thousands of plots is time‐consuming, expensive, and error‐prone, making selection for lodging resistance challenging in breeding programs ...
Srinivasa Reddy Mothukuri +8 more
wiley +1 more source
Abstract Although long‐read sequencing enables comprehensive genomic analysis, its potential is hindered by its reliance on the incomplete GRCh38 reference genome. GRCh38’s unresolved bases, structural errors, and haplotype mosaics introduce reference biases, leading to missed variants and false‐positive calls.
Zhenxian Zheng +6 more
wiley +1 more source
Systematic quantification and removal of host DNA contamination in 16S rRNA gene sequencing
Abstract 16S ribosomal RNA (rRNA) gene sequencing is a standard tool for microbial community analysis. Challenges can occur, particularly in low‐biomass samples, when host DNA triggers off‐target amplification. Low‐biomass microbiome studies are particularly vulnerable to contamination from host DNA, which can obscure microbial signals and bias ...
Till Birkner +4 more
wiley +1 more source
An electrochemical biosensing platform based on 1‐pyrenebutyric acid N‐hydroxysuccinimide ester (Pyr‐NHS) functionalized 3D graphene foam is developed for resolving amyloid beta (Aβ42 and Aβ40) biomarker ratios in human serum with femtomolar limits of detection, offering a foundational step forward in prospective point‐of‐care screening tools.
Muhsin Dogan +3 more
wiley +1 more source

