Mechanistic modeling of tumor immune microenvironment reveals strategies to enhance antibody-drug conjugates' efficacy. [PDF]
Harkos C +3 more
europepmc +1 more source
Operationalizing the Waste Hierarchy Though A Synthetic Performance Indicator: Evidence From Spain
ABSTRACT Ensuring compliance with the European Union (EU) waste hierarchy is essential for advancing circular economy objectives and meeting legally binding municipal solid waste (MSW) targets. This study develops and applies the Waste Hierarchy Achievement Synthetic Indicator (WHASI), an innovative synthetic index designed to assess territorial ...
Victor Mocholí +2 more
wiley +1 more source
Advanced drug delivery and PBPK modelling as translational tools for precision therapies in juvenile idiopathic arthritis. [PDF]
Cuquerella-Gilabert M +7 more
europepmc +1 more source
Sustainable Production Planning: Insights Into Factors, Models, and Solution Methods
ABSTRACT Effective resource management remains a major challenge for organizations seeking to balance economic efficiency with environmental and social responsibility. In this context, production planning becomes a strategic mechanism for integrating sustainability into industrial operations.
Daysi Ortiz +2 more
wiley +1 more source
Individualized dosing in the precision medicine era: a narrative review. [PDF]
Alsalloum MA +4 more
europepmc +1 more source
ABSTRACT The rapid expansion of renewable energy, particularly wind power, is expected to generate large volumes of composite waste from end‐of‐life (EoL) turbine blades in the coming decades. Managing this material represents a significant environmental and logistical challenge worldwide.
Plinio Centoamore +6 more
wiley +1 more source
By integrating game theory‐based combined weighting with a system dynamics model, this study systematically reveals the dominant role of agility and adaptability in the resilience of post‐disaster emergency material supply chains. ABSTRACT In light of the intricate dynamics and uncertain risk parameters inherent in the emergency materials supply chains,
Hao Sun, Longxiang Ma, Fuyu Wang
wiley +1 more source
The role of problem-solving and decision-making skills in linking critical thinking dispositions to perceptions of success. [PDF]
Akçay AO, Karahan E, Kara A.
europepmc +1 more source
Baselining Large Language Model Performance in Systems Engineering Using SysEngBench
ABSTRACT In the rapidly evolving field of artificial intelligence (AI), large language model s (LLMs) have demonstrated impressive capabilities in generating natural language. However, their proficiency in specialized domains, particularly in the field of systems engineering (SE), remains less explored and unquantified.
Ryan Bell +3 more
wiley +1 more source
Pharmacometric modeling of opioid disposition in pregnancy: a systematic review of PopPK and PBPK approaches, model limitations, and future directions. [PDF]
Zaidi SS +3 more
europepmc +1 more source

