Results 41 to 50 of about 1,951,824 (276)

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

On the anniversary of Professor Alexander Hramov [PDF]

open access: yesИзвестия высших учебных заведений: Прикладная нелинейная динамика
September 20, 2024 marks the 50th anniversary of Doctor of Physical and Mathematical Sciences, Professor Alexander Evgenievich Khramov, a brilliant scientist, a recognized specialist in the field of radiophysics, nonlinear dynamics and theory of complex ...
Kurkin, Semen Andreevich
doaj   +1 more source

A method for reducing animal use whilst maintaining statistical power in electrophysiological recordings from rodent nerves

open access: yesHeliyon, 2020
The stimulus evoked compound action potential, recorded from ex vivo nerve trunks such as the rodent optic and sciatic nerve, is a popular model system used to study aspects of nervous system metabolism.
Laura R. Rich   +4 more
doaj   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

A mathematical model of neuroimmune interactions in epileptogenesis for discovering treatment strategies

open access: yesiScience, 2022
Summary: The development of epilepsy (epileptogenesis) involves a complex interplay of neuronal and immune processes. Here, we present a first-of-its-kind mathematical model to better understand the relationships among these processes.
Danylo Batulin   +4 more
doaj   +1 more source

Miami Neuroscience Institute - Winter 2021

open access: yes, 2021
https://scholarlycommons.baptisthealth.net/bg-bh-neuroscience-news/1004/thumbnail ...
Miami Neuroscience Institute
core   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green   +6 more
wiley   +1 more source

Short report The DeDiMa battery: a tool for identifying students’ mathematical learning profiles

open access: yesHealth Psychology Report, 2014
Background The DeDiMa battery is designed for assessing students’ mathematical learning profiles, and it has been used to validate a 4-dimensional model for classifying mathematical learning difficulties.
Giannis Karagiannakis   +1 more
doaj   +1 more source

Quantitative systems pharmacology in neuroscience: Novel methodologies and technologies

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2021
The development and application of quantitative systems pharmacology models in neuroscience have been modest relative to other fields, such as oncology and immunology, which may reflect the complexity of the brain.
Peter Bloomingdale   +7 more
doaj   +1 more source

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