Results 21 to 30 of about 27,430 (264)

A Rigorous Analysis of Integro-Differential Operators with Non-Singular Kernels

Fractal and Fractional, 2023
Integro-differential operators with non-singular kernels have been much discussed among fractional calculus researchers. We present a mathematical study to clearly establish the rigorous foundations of this topic.
Arran Fernandez, Mohammed Al-Refai
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Generalized (τ, σ)-L-Derivations in Rings

Mathematics
Let τ and σ:X⟶X be automorphisms of an arbitrary associative ring X, and let L be a prime ideal of X. The main objective of this article is to combine the notions of generalized L-derivations and (τ,σ)-L-derivations by introducing and analyzing a novel ...
Hicham Saber, Zakia Z. Al-Amery, Radwan M. Al-omary, Khaled Aldwoah, Amer Alsulami, Muntasir Suhail   +5 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Evolutionary sequential genetic search technique-based cancer classification using fuzzy rough nearest neighbour classifier

Healthcare Technology Letters, 2018
Cancer is one of the deadly diseases of human life. The patient may likely to survive if the disease is diagnosed in its early stages. In this Letter, the authors propose a genetic search fuzzy rough (GSFR) feature selection algorithm, which is ...
Loganathan Meenachi, Srinivasan Ramakrishnan   +1 more
doaj   +1 more source

Analysis of series RL and RC circuits with time-invariant source using truncated M, Atangana beta and conformable derivatives

Journal of Ocean Engineering and Science, 2021
Complex processes of the physical world require novel and sophisticated mathematical notions to get deep insights. In this research analysis, two standard mathematical models for the series RL and RC circuits having time-invariant sources taken from the ...
Sania Qureshi, Mokhi Maan Chang, Asif Ali Shaikh   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A Study of Szász–Durremeyer-Type Operators Involving Adjoint Bernoulli Polynomials

Mathematics
This research work introduces a connection of adjoint Bernoulli’s polynomials and a gamma function as a sequence of linear positive operators. Further, the convergence properties of these sequences of operators are investigated in various functional ...
Nadeem Rao, Mohammad Farid, Rehan Ali
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source