Results 41 to 50 of about 550,186 (331)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

A Study of Szász–Durremeyer-Type Operators Involving Adjoint Bernoulli Polynomials

Mathematics
This research work introduces a connection of adjoint Bernoulli’s polynomials and a gamma function as a sequence of linear positive operators. Further, the convergence properties of these sequences of operators are investigated in various functional ...
Nadeem Rao, Mohammad Farid, Rehan Ali
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Operational Calculus of the Quantum Statistical Fermi–Dirac and Bose–Einstein Functions Leading to the Novel Fractional Kinetic Equations

Fractal and Fractional
The sun is a fundamental element of the natural environment, and kinetic equations are crucial mathematical models for determining how quickly the chemical composition of a star like the sun is changing. Taking motivation from these facts, we develop and
Asifa Tassaddiq, Carlo Cattani, Rabab Alharbi, Ruhaila Md Kasmani, Sania Qureshi   +4 more
doaj   +1 more source

Generalized k-Fractional Chebyshev-Type Inequalities via Mittag-Leffler Functions

Axioms, 2022
Mathematical inequalities have gained importance and popularity due to the application of integral operators of different types. The present paper aims to give Chebyshev-type inequalities for generalized k-integral operators involving the Mittag-Leffler ...
Zhiqiang Zhang, Ghulam Farid, Sajid Mehmood, Chahn-Yong Jung, Tao Yan   +4 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Lenard scheme for two dimensional periodic Volterra chain

, 2008
We prove that for compatible weakly nonlocal Hamiltonian and symplectic operators, hierarchies of infinitely many commuting local symmetries and conservation laws can be generated under some easily verified conditions no matter whether the generating ...
Wang, Jing Ping
core   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Modularity of Behaviours for Mathematical Operational Semantics

Electronic Notes in Theoretical Computer Science, 2004
AbstractSome years ago, Turi and Plotkin gave a precise mathematical formulation of a notion of structural operational semantics: their formulation is equivalent to a distributive law of the free monad on a signature over the cofree copointed endofunctor on a behaviour endofunctor. From such a distributive law, one can readily induce a distributive law
Marco Kick, A. John Power
openaire   +2 more sources

An Application of Multiple Erdélyi–Kober Fractional Integral Operators to Establish New Inequalities Involving a General Class of Functions

Fractal and Fractional
This research aims to develop generalized fractional integral inequalities by utilizing multiple Erdélyi–Kober (E–K) fractional integral operators. Using a set of j, with (j∈N) positively continuous and decaying functions in the finite interval a≤t≤x ...
Asifa Tassaddiq, Rekha Srivastava, Rabab Alharbi, Ruhaila Md Kasmani, Sania Qureshi   +4 more
doaj   +1 more source