Results 31 to 40 of about 150,441 (264)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Lange on Mathematical Explanation, Grounding, and the Divergence Thesis
CríticaMark Lange has defended the view that mathematical explanation and grounding explanation diverge. In this paper, I argue that at least one type of grounding relation is immune to his criticisms. After fixing a minimal separatist theory of ground, I show
Mohammad Maarefi
doaj +1 more source
Learning from Euler. From Mathematical Practice to Mathematical Explanation
Philosophia Scientiæ, 2012 In his "Découverte d'un nouveau principe de mécanique" (1750) Euler offered, for the first time, a proof of the so-called Euler's Theorem. In this paper I will focus on Euler's original proof and I will show how a look at Euler's practice as a ...
Daniele Molinini
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Practice, Constraint, and Mathematical Concepts
Philosophia Scientiæ, 2012 In this piece I articulate and defend a conception of mathematical practice and mathematical subject-matter, which is responsive both to a sensible pluralism concerning the connection between inferential practices and guiding interests, on the one hand ...
Mark C. R. Smith
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Longitudinal study of gastroesophageal reflux and erosive tooth wear
BMC Gastroenterology, 2017 Background Approximately 60% of patients presenting to dentists with erosive tooth wear have significant gastroesophageal reflux (GERD), despite minor reflux symptoms.
Clive H. Wilder-Smith +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source