Results 41 to 50 of about 1,378,245 (304)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Mathematical game performance as an indicator of deliberate practice

open access: yesInternational Journal of Serious Games, 2023
The traditional classroom setting presents challenges when it comes to strengthening adaptive expertise in mathematics education through deliberate practice.
Jake McMullen   +4 more
doaj   +1 more source

Teachers’ Accounts of Developing Mathematical Resilience in the Classroom [PDF]

open access: yes, 2017
This paper reports on a professional development programme in mathematical resilience, and the experiences of the teachers taking part. The programme introduced the teachers to the construct of mathematical resilience, and explained how it was relevant ...
Lee, Clare, Ward-Penny, Robert
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Practice, Constraint, and Mathematical Concepts

open access: yesPhilosophia Scientiæ, 2012
In this piece I articulate and defend a conception of mathematical practice and mathematical subject-matter, which is responsive both to a sensible pluralism concerning the connection between inferential practices and guiding interests, on the one hand ...
Mark C. R. Smith
doaj   +1 more source

Discussion of "Impact of Frequentist and Bayesian Methods on Survey Sampling Practice: A Selective Appraisal" by J. N. K. Rao

open access: yes, 2011
Discussion of "Impact of Frequentist and Bayesian Methods on Survey Sampling Practice: A Selective Appraisal" by J. N. K. Rao [arXiv:1108.2356]Comment: Published in at http://dx.doi.org/10.1214/11-STS346C the Statistical Science (http://www.imstat.org ...
Slud, Eric
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Longitudinal study of gastroesophageal reflux and erosive tooth wear

open access: yesBMC Gastroenterology, 2017
Background Approximately 60% of patients presenting to dentists with erosive tooth wear have significant gastroesophageal reflux (GERD), despite minor reflux symptoms.
Clive H. Wilder-Smith   +3 more
doaj   +1 more source

Of the use of the “English sector” in trigonometry: what amount of mathematical training was necessary in the 18th century? [PDF]

open access: yes, 2016
In 1723 Edmund Stone published The construction and principal uses of mathematical instruments, which was essentially a translation from the French of Bion’s Traité de la construction et des principaux usages des instrumens de mathématique (1709).
Blanco Abellán, Mónica
core   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

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