Results 101 to 110 of about 454,868 (300)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
, 2015 We present a Bayesian method for characterizing the mating system of populations reproducing through a mixture of self-fertilization and random outcrossing.
Avise, John C. +8 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 1987 A daze fastener system for connecting two or more structural elements wherein the structural elements and fastener parts have substantially different coefficient of thermal expansion physical property characteristics is employed in this invention.
Davis, Randall C. +2 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Why Monogamy? A Review of Potential Ultimate Drivers
Frontiers in Ecology and Evolution, 2018 The existence of monogamy in animals is perplexing from an evolutionary perspective. If individuals: (1) have the opportunity to mate with more than one individual and (2) doing so provides fitness benefits (e.g., indirect benefits, increased mating ...
Hope Klug
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Outcrossing in Caenorhabditis elegans increases in response to food limitation
Ecology and EvolutionTheory predicts that organisms should diversify their offspring when faced with a stressful environment. This prediction has received empirical support across diverse groups of organisms and stressors.
Samuel P. Slowinski +5 more
doaj +1 more source
Ornamental HorticultureVanilla planifolia Jacks. is an orchid of great economic interest, classified as endangered. The limited genetic variation of this species has been primarily attributed to its clonal propagation.
Zelzin Eréndira Fernández-Villa +2 more
doaj +1 more source
Mating system ofMicrocebus murinus
American Journal of Primatology, 1999 Microcebus murinus, a small nocturnal lemur from Madagascar, has retained features of ancient primates. Based on these ancestral traits, its social organization has often been used as a model for early primate social systems. In captivity it breeds polygynously, i.e., one male mates with several females, while females usually copulate only with the ...
openaire +3 more sources