Results 131 to 140 of about 13,912,764 (337)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Journal of Pure and Applied MicrobiologyCandida species are major opportunistic fungal causative agents for significant infections. While C. albicans is considered the most widespread and virulent species, the clinical importance of non-albicans Candida species has substantially risen.
Haya Radwan, Ghaleb Adwan
doaj +1 more source
Plant Protection Science, 2006 A total of 199 Phytophthora infestans isolates were obtained from leaves, tubers and fruits of infected crops of potato and tomato in different regions of the Czech Republic in 2003, 2004 and 2005.
Jana Mazáková +5 more
doaj +1 more source
Isolation and characterisation of the mating-type (MAT ) locus from Rhynchosporium secalis
, 2003 The mating-type (MAT) genes from Rhynchosporium secalis were isolated using PCR-based methods. Characterisation of the MAT idiomorphs suggests that R. secalis is closely related to the discomycetes Pyrenopeziza brassicae and Tapesia yallundae in terms of
Fitt, B. D. L. +3 more
core +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
, 2013 The aim of this study was to investigate the basis to male mating decisions in two related species of bitterling: Rhodeus ocellatus and R. amarus. Bitterling have a resource-based mating system; females lay eggs in the gills of live freshwater mussels ...
Casalini, Mara
core
Mating type tests on plates with wild type testers
, 1971 Mating type tests on plates with wild type ...
J. F. Feldman +3 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
The Stochastic Encounter-Mating Model
, 2016 We propose a new model of permanent monogamous pair formation in zoological populations with multiple types of females and males. According to this model, animals randomly encounter members of the opposite sex at their so-called firing times to form ...
Gün, Onur, Yilmaz, Atilla
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source