Results 31 to 40 of about 206,549 (259)
A coupled process of same- and opposite-sex mating generates polyploidy and genetic diversity in Candida tropicalis. [PDF]
PLoS Genetics, 2018 Sexual reproduction is a universal mechanism for generating genetic diversity in eukaryotes. Fungi exhibit diverse strategies for sexual reproduction both in nature and in the laboratory.
Han Du +4 more
doaj +1 more source
Peer Community Journal, 2023 Large regions of suppressed recombination having extended over time occur in many organisms around genes involved in mating compatibility (sex-determining or mating-type genes).
Tezenas, Emilie +3 more
doaj +1 more source
Linkage mapping identifies the sex determining region as a single locus in the Pennate diatom Seminavis robusta. [PDF]
PLoS ONE, 2013 The pennate diatom Seminavis robusta, characterized by an archetypical diatom life cycle including a heterothallic mating system, is emerging as a model system for studying the molecular regulation of the diatom cell and life cycle.
Ives Vanstechelman +4 more
doaj +1 more source
Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway.
PLoS Biology, 2019 While sexual reproduction is pervasive in eukaryotic cells, the strategies employed by fungal species to achieve and complete sexual cycles is highly diverse and complex.
Guobo Guan +11 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Selfing mutants link Ku proteins to mating type determination in Tetrahymena.
PLoS Biology, 2020 Recognition of self and nonself is important for outcrossing organisms, and different mating types establish the barrier against self-mating. In the unicellular ciliate T.
I-Ting Lin, Meng-Chao Yao
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
You’re Just My Type: Mate Choice and Behavioral Types [PDF]
Trends in Ecology & Evolution, 2020 Consistent individual differences in behavior [i.e., behavioral types (BTs)], are common across the animal kingdom. Consistency can make behavior an adaptive trait for mate choice decisions. Here, we present a conceptual framework to explain how and why females might evaluate a male's BT before mating. Because BTs are consistent across time or context,
Amelia A, Munson +3 more
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source