Results 101 to 110 of about 4,872,302 (299)

Molecular characterization of environmental Cryptococcus neoformans isolated in Vitoria, ES, Brazil Caracterização molecular de cepas ambientais de Cryptococcus neoformans isoladas em Vitória, ES, Brasil

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2008
Cryptococcus neoformans is the major cause of fungal meningitis, a potentially lethal mycosis. Bird excreta can be considered a significant environmental reservoir of this species in urban areas, thirty-three samples of pigeon excreta were collected ...
Mariceli Araujo Ribeiro   +1 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Molecular type, mating type, allele types and sequence types of Colombian Cryptococcus gattii clinical strains.

open access: yes, 2014
Note: *New allele or sequence type.Molecular type, mating type, allele types and sequence types of Colombian Cryptococcus gattii clinical strains.
Patricia Escandón (663964)   +5 more
core   +1 more source

Identification and Functional Analysis of the Pheromone Response Factor Gene of Sporisorium scitamineum

open access: yesFrontiers in Microbiology, 2019
The sugarcane smut fungus Sporisorium scitamineum is bipolar and produces sporidia of two different mating types. During infection, haploid cells of opposite mating types can fuse to form dikaryotic hyphae that can colonize plant tissue.
Guining Zhu   +13 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

The Stochastic Encounter-Mating Model

open access: yes, 2016
We propose a new model of permanent monogamous pair formation in zoological populations with multiple types of females and males. According to this model, animals randomly encounter members of the opposite sex at their so-called firing times to form ...
Gün, Onur, Yilmaz, Atilla
core   +1 more source

Parent-offspring correlations under full-sib and parent-offspring mating systems

open access: yes, 1975
A study of the parent-offspring correlations under full-sib mating and parent-offspring mating system has been conducted. A general theory for obtaining the correlation between one parent and k offspring, as well as the correlation between both the ...
George, K. C., Narain, P.
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Distribution of A. flavus mating types across states, treatments, and years 1.

open access: yes, 2022
Distribution of A. flavus mating types across states, treatments, and years 1.
Charles P. Woloshuk (4594147)   +13 more
core   +1 more source

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