Results 81 to 90 of about 136,854 (259)

Mating Types of Ustilago esculenta Infecting Zizania latifolia Cultivars in Japan Are Biased towards MAT-2 and MAT-3. [PDF]

Microbes Environ, 2023
Chigira Y, Sasaki N, Komatsu K, Mashimo K, Tanaka S, Numamoto M, Moriyama H, Motobayashi T.   +7 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Genotyping of the MTL loci and susceptibility to two antifungal agents of Candida glabrata clinical isolates

Memorias do Instituto Oswaldo Cruz, 2009
The opportunistic fungal pathogen Candida glabrata is the second most common isolate from bloodstream infections worldwide and is naturally less susceptible to the antifungal drug fluconazole than other Candida species. C.
María Teresa Lavaniegos-Sobrino, Candy Y Ramírez-Zavaleta, Alfredo Ponce de León, José Sifuentes-Osornio, Miriam Bobadilla-Del Valle, Andrea Rangel-Cordero, Alejandro De Las Peñas, Irene Castaño   +7 more
doaj   +1 more source

Identification and comparison of biological characteristics and pathogenicity of different mating types of V. dahliae isolated from potato and sunflower. [PDF]

Sci Rep, 2022
Yan N, Addrah ME, Zhang Y, Jia R, Kang L, Zhao J, Zhang J.   +6 more
europepmc   +1 more source

The evolution of mating type switching.

Evolution; international journal of organic evolution, 2016
Predictions about the evolution of sex determination mechanisms have mainly focused on animals and plants, whereas unicellular eukaryotes such as fungi and ciliates have received little attention. Many taxa within the latter groups can stochastically switch their mating type identity during vegetative growth.
Hadjivasiliou, Z, Pomiankowski, A, Kuijper, B   +2 more
openaire   +4 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Mating-Type Analysis in Diaporthe Isolates from Soybean in Central Europe

Journal of Fungi
Species of the genus Diaporthe have a mating-type system with the two mating types MAT1-1 and MAT1-2, like other ascomycetes. They can either be heterothallic, which means that any isolate only possesses one of the two mating types and needs a mating ...
Behnoush Hosseini, Lena Sophia Käfer, Tobias Immanuel Link   +2 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Metabolomic and Physiological Changes in Fagus sylvatica Seedlings Infected with Phytophthora plurivora and the A1 and A2 Mating Types of P. ×cambivora. [PDF]

J Fungi (Basel), 2022
Corcobado T, Milenković I, Saiz-Fernández I, Kudláček T, Plichta R, Májek T, Bačová A, Ďatková H, Dálya LB, Trifković M, Mureddu D, Račko V, Kardošová M, Ďurkovič J, Rattunde R, Jung T.   +15 more
europepmc   +1 more source