Results 101 to 110 of about 9,281 (250)
Synthesis, characterization and in vitro biological evaluation of two matrine derivatives
Scientific Reports, 2018 Matrine is a traditional Chinese medicine and botanical pesticide with broad biological activities, including pharmacological and agricultural activities.
Xingan Cheng +9 more
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Matrine: A Promising Natural Product With Various Pharmacological Activities
Frontiers in Pharmacology, 2020 Matrine is an alkaloid isolated from the traditional Chinese medicine Sophora flavescens Aiton. At present, a large number of studies have proved that matrine has an anticancer effect can inhibit cancer cell proliferation, arrest cell cycle, induce ...
Hong Zhang +8 more
doaj +1 more source
Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation. [PDF]
PLoS ONE, 2012 Acute myeloid leukemia (AML) is a hematological malignancy characterized by a rapid increase in the number of immature myeloid cells in bone marrow. Despite recent advances in the treatment, AML remains an incurable disease.
Shenghui Zhang +8 more
doaj +1 more source
Carnosol Modulates Th17 Cell Differentiation and Microglial Switch in Experimental Autoimmune Encephalomyelitis [PDF]
, 2018 Medicinal plants as a rich pool for developing novel small molecule therapeutic medicine have been used for thousands of years. Carnosol as a bioactive diterpene compound originated from Rosmarinus officinalis (Rosemary) and Salvia officinalis, herbs ...
Fei Zhang +10 more
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Journal of Veterinary ResearchIntroduction Bovine viral diarrhoea virus (BVDV) can cause diarrhoea (BVD) in an animal herd, leading to heavy economic losses. There are limited drugs available for treating and controlling BVD.
D. Cai +8 more
semanticscholar +1 more source
Advances in Atopic Dermatitis Treatment: From Pathogenesis to Natural Product‐Based Therapies
Phytotherapy Research, Volume 39, Issue 10, Page 4444-4473, October 2025.NPs improve atopic dermatitis mainly include flavonoids, phenols, glycosides, alkaloids, and others. ABSTRACT Atopic dermatitis (AD), a widespread and chronic inflammatory skin disorder, profoundly affects patients' quality of life, imposes significant psychological strain, and adds to the public health burden.
Xinyun Fan +8 more
wiley +1 more source
Frontiers in Pharmacology, 2019 Matrine, an alkaloid compound isolated from the medicinal plant Sophora flavescens, inhibits many types of cancer proliferation. However, the precise mechanism of the matrine antihuman chronic myeloid leukemia remains unclear.
Guibin Lin +7 more
doaj +1 more source
Phytopharmacology and phytotherapy of regulatory T cells: A new approach to treat multiple sclerosis [PDF]
, 2016 Multiple sclerosis (MS) is a disorder of central nervous system characterized by demyelination, inflammation, and axonal injury. Regulatory T cells (Tregs) have been defined as CD4+CD25+FoxP3+ T-cells that play a critical role in maintaining self ...
Asadi-Samani, Majid. +3 more
core
Optimal management for alcoholic liver disease: Conventional medications, natural therapy or combination? [PDF]
, 2016 © The Author(s) 2016. Alcohol consumption is the principal factor in the pathogenesis of chronic liver diseases. Alcoholic liver disease (ALD) is defined by histological lesions on the liver that can range from simple hepatic steatosis to more advanced ...
Kim, MS, Ong, M, Qu, X
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Thoracic Cancer, Volume 16, Issue 19, October 2025.Radiation‐induced lung injury (RILI) is a common complication of thoracic radiotherapy, and Qingdi mixture (QDM) has shown efficacy in its prevention. Through network pharmacology, molecular docking, and experimental validation, QDM was found to mitigate RILI primarily by inhibiting the NF‐κB signaling pathway and reducing inflammatory cytokines ...
Haoran Liu +8 more
wiley +1 more source