Results 61 to 70 of about 4,760 (206)
Therapeutic effects of matrine on primary and metastatic breast cancer
, 2010 Matrine, one of the main components extracted from a traditional Chinese herb, Sophora flavescens Ait, has displayed anti-cancer activity in several types of cancer cells.
S Pan (13147035) +7 more
core +2 more sources
Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.Integrative omics strengthens target credibility by combining causal, functional, pharmacological and tissue‐context evidence. Go, refine and stop decisions convert multi‐omics findings into actionable translational choices. Biomarker readiness requires analytical validity, clinical validity, utility and implementation within a defined context of use ...
Ruba Altahla +7 more
wiley +1 more source
Stereostructures overlay of OS and matrine.
, 2013 (The OS was labeled as red and matrine as green).
Jian-Yong Li (424635) +5 more
core +1 more source
SIRT3‐Dependent Actions of Berberine: From Molecular Therapies to Toxicity
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.This study reveals that berberine's therapeutic versatility in metabolic, cardiovascular, and hepatic disorders stems from its modulation of the mitochondrial protein Sirt3. Understanding this mechanism explains both its broad efficacy and its organ‐specific toxicity, positioning berberine as a promising mitochondrial epigenetic modulator whose ...
Dareuosh Shackebaei +4 more
wiley +1 more source
Matrine alkaloids modulating DNA damage repair in chemoresistant non-small cell lung cancer cells
BMC CancerBackground Non-small cell lung cancer (NSCLC) presents a significant challenge in the medical field due to its high incidence and resistance to chemotherapy. Chemoresistance in NSCLC diminishes treatment efficacy and contributes to poor patient outcomes.
Fengping Wang +5 more
doaj +1 more source
Isolation and identification of a matrine-producing fungal strain from petroleum-contaminated soil
浙江大学学报. 农业与生命科学版, 2015 Matrine is one of the quinolizidine alkaloids. It is widely used as broad-spectrum agricultural pesticides, which exists mainly in roots of leguminous plants.
Mao Dongxia +6 more
doaj +1 more source
Fibulin‐1 Improves Caerulein‐Induced Acute Pancreatitis In Vitro by Inhibiting Ferroptosis
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.FBLN1 exhibited lower expression in acute pancreatitis. Moreover, FBLN1 inhibited inflammatory injury and ferroptosis in Caerulein‐triggered AR42J cells. FBLN1 can activate the NRF2/HO‐1 pathway. ABSTRACT Acute pancreatitis is an inflammatory disease of the pancreas that is often accompanied by various complications, which seriously impair patient ...
Xiaowei Mai +5 more
wiley +1 more source
Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives
Precision Medical Sciences, Volume 15, Issue 3, Page 206-226, September 2026.Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley +1 more source
AnimalsBacterial intestinal infections, such as porcine colibacillosis, have caused large economic losses to the global pig industry every year [...]
Ruonan Li +8 more
openaire +3 more sources
, 2022 Hepatocellular carcinoma (HCC) is a complex issue in cancer treatment in the world at present. Matrine is the main active ingredient isolated from Sophora flavescens air and possesses excellent antitumor effects in HCC.
Chuanzhi Duan (5647544) +9 more
core +1 more source