Results 51 to 60 of about 4,760 (206)

Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitro and in vivo [PDF]

, 2022
Matrine is a quinazoline alkaloid extracted from Sophora flavescens. The aim of the present study was to determine whether matrine can induce autophagy in the human HeLa and SiHa cervical cancer cell lines in vitro and in vivo.
Li, Mu, Chang, Lihua, Zhang, Hua, Xi, Yuyan, Wu, Xiaoling, Qian, Wenjun, Zhang, Fan   +6 more
core   +1 more source

Biological Impact and Enzyme Activities of Spodoptera litura (Lepidoptera: Noctuidae) in Response to Synergistic Action of Matrine and Beauveria brongniartii

Frontiers in Physiology, 2020
Matrine, a naturally occurring heterocyclic compound, has been shown to enhance the pathogenicity of the entomopathogenic fungus Beauveria brongniartii against Spodoptera litura.
Jianhui Wu, Jiaying Li, Can Zhang, Xintong Yu, Andrew G. S. Cuthbertson, Shaukat Ali   +5 more
doaj   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Matrine–Tea Saponin Synergism Involves Suppressed Detoxification and Digestion in a Leaf Beetle

Integrative Zoology, EarlyView.
Tea saponin and matrine showed synergistic toxicity against Plagiodera versicolora. Combined exposure suppressed digestion‐ and detoxification‐related processes, while silencing the trypsin gene Pver105950 and chitinase gene Pver001190 increased larval susceptibility to tea saponin and matrine, respectively.
Owais Khan, Xiayu Li, Yanping Zhang, Runhua Han, Letian Xu   +4 more
wiley   +1 more source

Stereostructures of matrine and sophoridine [34].

, 2013
Stereostructures of matrine and sophoridine [34].
Jian-Yong Li (424635), Ya-Jun Yang (119016), Ji-Yu Zhang (5007728), Bing Li (43671), Yu-Rong Liu (502012), Xi-Wang Liu (502011)   +5 more
core   +1 more source

Matrine inhibits cell growth, migration, invasion and promotes autophagy in hepatocellular carcinoma by regulation of circ_0027345/miR-345-5p/HOXD3 axis

Cancer Cell International, 2020
Background Matrine has been reported to exert anti-tumor effects in multiple types of cancers containing hepatocellular carcinoma (HCC). However, the anti-tumor molecular mechanisms of matrine in HCC is still not fully revealed.
Shaobing Lin, Jie Zhuang, Liping Zhu, Zongsheng Jiang   +3 more
doaj   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, Volume 13, Issue 59, 23 October 2026.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Table1_Computational Metabolomics Reveals the Potential Mechanism of Matrine Mediated Metabolic Network Against Hepatocellular Carcinoma.docx

, 2022
Hepatocellular carcinoma (HCC) is a complex issue in cancer treatment in the world at present. Matrine is the main active ingredient isolated from Sophora flavescens air and possesses excellent antitumor effects in HCC.
Chuanzhi Duan (5647544), Yupeng Chen (2822183), Li Gao (131516), Xiangmin Ye (13137111), Daogang Guan (461068), Aiping Lu (492389), Chuanhui Yin (12057800), Qing Ren (5596727), Kexin Wang (758568), Xuemei Qin (620090)   +9 more
core   +1 more source

The Pharmacological Studies on Matrine and Oxymatrine

YAKUGAKU ZASSHI, 2000
Matrine and oxymatrine, major components of Sophora flavescens, were confirmed to have a protective effect on restraint and water immersion stress ulcer in mice. Oxymatrine inhibits the formation of some experimental gastric ulcer, pylorus ligation ulcer and indomethacin ulcer, which are considered to relate to acid secretion. Oxymatrine decreases acid
openaire   +3 more sources

Investigation of Microemulsion System for Transdermal Delivery of Matrine

, 2011
A new O/W microemulsion system for transdermal matrine delivery was developed in order to provide clinical medication of matrine with a more convenient,reasonable and effective new form.Various factors were investigated including solubility of matrine ...
Hong Wei, Zheng Fu, Jie Mu, Rui Chen Guo
core   +1 more source