Results 41 to 50 of about 4,598 (207)

Matrin 3 in neuromuscular disease: physiology and pathophysiology [PDF]

JCI Insight, 2021
RNA-binding proteins (RBPs) are essential factors required for the physiological function of neurons, muscle, and other tissue types. In keeping with this, a growing body of genetic, clinical, and pathological evidence indicates that RBP dysfunction and/or gene mutation leads to neurodegeneration and myopathy.
Ahmed M. Malik, Sami J. Barmada
openaire   +3 more sources

Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway

Acta Pharmaceutica Sinica B, 2019
Oxidative stress and cardiomyocyte apoptosis are involved in the pathogenesis of doxorubicin (DOX)-induced cardiotoxicity. Matrine is well-known for its powerful anti-oxidant and anti-apoptotic capacities.
Can Hu, Xin Zhang, Wenying Wei, Ning Zhang, Haiming Wu, Zhenguo Ma, Lingli Li, Wei Deng, Qizhu Tang   +8 more
doaj   +1 more source

Synergistic Interaction between the Entomopathogenic Fungus Akanthomyces attenuatus (Zare & Gams) and the Botanical Insecticide Matrine against Megalurothrips usitatus (Bagrall)

Journal of Fungi, 2021
The excessive use of synthetic chemicals for Megalurothrips usitatus (Bagrall) management has resulted in the development of insecticide resistance as well as adverse effects to the natural ecosystem.
Jianhui Wu, Bo Yang, Xiaochen Zhang, Andrew G. S. Cuthbertson, Shaukat Ali   +4 more
doaj   +1 more source

Rapid determination of matrine and oxymatrine in honey

, 2022
Objective: This study aimed to establish a new method for the determination of matrine and oxymatrine in honey by UPLC-MS/MS. Methods: The honey was dissolved in water, and the liquid-liquid extraction pretreatment technology was adopted.
Hui-hua, JING, Yan-ying, FENG, Deng-hui, JIANG, JIANG Deng-hui, FENG Yan-ying, Liang-liang, WANG, Jun, XIANG, WANG Yun-hao, WANG Liang-liang, JING Hui-hua, Yun-hao, WANG, XIANG Jun   +11 more
core   +1 more source

Matrine Ameliorates Colorectal Cancer in Rats via Inhibition of HMGB1 Signaling and Downregulation of IL-6, TNF-α, and HMGB1

Journal of Immunology Research, 2018
Matrine may be protective against colorectal cancer (CRC), but how it may work is unclear. Thus, we explored the underlying mechanisms of matrine in CRC.
Huizhen Fan, Chunyan Jiang, Baoyuan Zhong, Jianwen Sheng, Ting Chen, Qingqing Chen, Jingtao Li, Hongchuan Zhao   +7 more
doaj   +1 more source

Role and mechanism of matrine alone and combined with acitretin for HaCaT cells and psoriasis-like murine models

Chinese Medical Journal, 2019
. Background:. Acitretin and matrine have been used in the treatment of psoriasis in China. This study was designed to investigate the role and related mechanisms of matrine alone and in combination with acitretin in the treatment of psoriasis in vitro ...
Wei-Wei Jiang, Yi-Meng Wang, Xiao-Yu Wang, Qian Zhang, Si-Man Zhu, Chun-Lei Zhang, Li-Shao Guo   +6 more
doaj   +1 more source

Study on mechanism of matrine in treatment of COVID-19 combined with liver injury by network pharmacology and molecular docking technology

Drug Delivery, 2021
The aim of the present study was to investigate the pharmacological mechanism of matrine in treatment of COVID-19 combined with liver injury. Potential targets related to matrine, COVID-19 and liver injury were identified from several databases.
Fangzhou Liu, Yuanbai Li, Yang Yang, Meng Li, Yu Du, Yiying Zhang, Jing Wang, Yujing Shi   +7 more
doaj   +1 more source

Sedative Effect ofSophora flavescensand Matrine [PDF]

Biomolecules & Therapeutics, 2017
The present study investigated the sedative effects of Sophora flavescens (SF) and its bioactive compound, matrine through performing locomotor activity test and the electroencephalography (EEG) analysis in the rat. The underlying neural mechanism of their beneficial effects was determined by assessing c-Fos immunoreactivity and serotonin (5-HT) in the
Lee, Hyun-ju, Lee, Sun-young, Jang, Daehyuk, Chung, Sun-Yong, Shim, Insop   +4 more
openaire   +2 more sources

Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome

Veterinary Research, 2019
Our previous studies demonstrated that matrine directly acts on the replication process of porcine reproductive and respiratory syndrome virus (PRRSV). Matrine inhibits viral replication and is also associated with the NF-κB signalling pathway.
Panpan Sun, Na Sun, Wei Yin, Yaogui Sun, Kuohai Fan, Jianhua Guo, Ajab Khan, Yongming He, Hongquan Li   +8 more
doaj   +1 more source

Matrine Targets BTF3 to Inhibit the Growth of Canine Mammary Tumor Cells

, 2023
The canine mammary tumor model is more suitable for studying human breast cancer, and the safety concentrations of matrine and the biotin-labeled matrine probe were determined in canine primary mammary epithelial cells, and then selected canine mammary ...
Zijian Feng, Huizhen Yang, Hua Zhang, Wei Yin, Hongquan Li, Yaogui Sun, Fida Noor, Zhenbiao Zhang, Panpan Sun, Jia Zhong, Kuohai Fan, Na Sun   +11 more
core   +1 more source