Results 21 to 30 of about 3,599 (178)

Comparative transcriptome analysis reveals differences in gene expression in whitefly following individual or combined applications of Akanthomyces attenuatus (Zare & Gams) and matrine

BMC Genomics, 2022
Background Bemisia tabaci Gennadius (Hemiptera: Aleyrodidae) is a serious pest of crops in different regions of the world. Our recent studies on the joint application of Akanthomyces attenuatus (a pathogenic insect fungus) and matrine (a botanical ...
Jianhui Wu, Tingfei Sun, Muhammad Hamid Bashir, Baoli Qiu, Xingmin Wang, Shaukat Ali   +5 more
doaj   +1 more source

Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway

Cancer Medicine, 2018
Background Matrine, a traditional Chinese medicine, has recently been shown to have antitumor properties in diverse cancer cells. Here, we explored the effect of matrine on human glioblastoma multiforme (GBM) cells.
Wenjing Zhou, Jiwei Wang, Qichao Qi, Zichao Feng, Bin Huang, Anjing Chen, Di Zhang, Wenjie Li, Qing Zhang, Rolf Bjerkvig, Xingang Li, Jian Wang   +11 more
doaj   +1 more source

Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway

Acta Pharmaceutica Sinica B, 2019
Oxidative stress and cardiomyocyte apoptosis are involved in the pathogenesis of doxorubicin (DOX)-induced cardiotoxicity. Matrine is well-known for its powerful anti-oxidant and anti-apoptotic capacities.
Can Hu, Xin Zhang, Wenying Wei, Ning Zhang, Haiming Wu, Zhenguo Ma, Lingli Li, Wei Deng, Qizhu Tang   +8 more
doaj   +1 more source

Synergistic Interaction between the Entomopathogenic Fungus Akanthomyces attenuatus (Zare & Gams) and the Botanical Insecticide Matrine against Megalurothrips usitatus (Bagrall)

Journal of Fungi, 2021
The excessive use of synthetic chemicals for Megalurothrips usitatus (Bagrall) management has resulted in the development of insecticide resistance as well as adverse effects to the natural ecosystem.
Jianhui Wu, Bo Yang, Xiaochen Zhang, Andrew G. S. Cuthbertson, Shaukat Ali   +4 more
doaj   +1 more source

Matrine Ameliorates Colorectal Cancer in Rats via Inhibition of HMGB1 Signaling and Downregulation of IL-6, TNF-α, and HMGB1

Journal of Immunology Research, 2018
Matrine may be protective against colorectal cancer (CRC), but how it may work is unclear. Thus, we explored the underlying mechanisms of matrine in CRC.
Huizhen Fan, Chunyan Jiang, Baoyuan Zhong, Jianwen Sheng, Ting Chen, Qingqing Chen, Jingtao Li, Hongchuan Zhao   +7 more
doaj   +1 more source

Role and mechanism of matrine alone and combined with acitretin for HaCaT cells and psoriasis-like murine models

Chinese Medical Journal, 2019
. Background:. Acitretin and matrine have been used in the treatment of psoriasis in China. This study was designed to investigate the role and related mechanisms of matrine alone and in combination with acitretin in the treatment of psoriasis in vitro ...
Wei-Wei Jiang, Yi-Meng Wang, Xiao-Yu Wang, Qian Zhang, Si-Man Zhu, Chun-Lei Zhang, Li-Shao Guo   +6 more
doaj   +1 more source

Study on mechanism of matrine in treatment of COVID-19 combined with liver injury by network pharmacology and molecular docking technology

Drug Delivery, 2021
The aim of the present study was to investigate the pharmacological mechanism of matrine in treatment of COVID-19 combined with liver injury. Potential targets related to matrine, COVID-19 and liver injury were identified from several databases.
Fangzhou Liu, Yuanbai Li, Yang Yang, Meng Li, Yu Du, Yiying Zhang, Jing Wang, Yujing Shi   +7 more
doaj   +1 more source

Matrin 3 in neuromuscular disease: physiology and pathophysiology [PDF]

JCI Insight, 2021
RNA-binding proteins (RBPs) are essential factors required for the physiological function of neurons, muscle, and other tissue types. In keeping with this, a growing body of genetic, clinical, and pathological evidence indicates that RBP dysfunction and/or gene mutation leads to neurodegeneration and myopathy.
Ahmed M. Malik, Sami J. Barmada
openaire   +3 more sources

Sedative Effect ofSophora flavescensand Matrine [PDF]

Biomolecules & Therapeutics, 2017
The present study investigated the sedative effects of Sophora flavescens (SF) and its bioactive compound, matrine through performing locomotor activity test and the electroencephalography (EEG) analysis in the rat. The underlying neural mechanism of their beneficial effects was determined by assessing c-Fos immunoreactivity and serotonin (5-HT) in the
Lee, Hyun-ju, Lee, Sun-young, Jang, Daehyuk, Chung, Sun-Yong, Shim, Insop   +4 more
openaire   +2 more sources

Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome

Veterinary Research, 2019
Our previous studies demonstrated that matrine directly acts on the replication process of porcine reproductive and respiratory syndrome virus (PRRSV). Matrine inhibits viral replication and is also associated with the NF-κB signalling pathway.
Panpan Sun, Na Sun, Wei Yin, Yaogui Sun, Kuohai Fan, Jianhua Guo, Ajab Khan, Yongming He, Hongquan Li   +8 more
doaj   +1 more source