Results 1 to 10 of about 4,598 (207)

Matrine–Tea Saponin Synergism Involves Suppressed Detoxification and Digestion in a Leaf Beetle

Integrative Zoology, EarlyView.
Tea saponin and matrine showed synergistic toxicity against Plagiodera versicolora. Combined exposure suppressed digestion‐ and detoxification‐related processes, while silencing the trypsin gene Pver105950 and chitinase gene Pver001190 increased larval susceptibility to tea saponin and matrine, respectively.
Owais Khan, Xiayu Li, Yanping Zhang, Runhua Han, Letian Xu   +4 more
wiley   +1 more source

Fibulin‐1 Improves Caerulein‐Induced Acute Pancreatitis In Vitro by Inhibiting Ferroptosis

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
FBLN1 exhibited lower expression in acute pancreatitis. Moreover, FBLN1 inhibited inflammatory injury and ferroptosis in Caerulein‐triggered AR42J cells. FBLN1 can activate the NRF2/HO‐1 pathway. ABSTRACT Acute pancreatitis is an inflammatory disease of the pancreas that is often accompanied by various complications, which seriously impair patient ...
Xiaowei Mai, ShuLiu He, YangYang Li, Lei Zhang, QiZhong Xu, YinSheng Wen   +5 more
wiley   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, Volume 15, Issue 3, Page 206-226, September 2026.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Squash silverleaf disorder and whitefly (Bemisia tabaci MEAM1) infestation: Implications for plant disease management in a changing climate

Annals of Applied Biology, Volume 189, Issue 2, September 2026.
Squash Silverleaf Disorder (SLD) is growing in its economic impact due to the invasive behaviour of the silverleaf whitefly (Bemisia tabaci MEAM1). In this review we summarize what is currently known about the whitefly‐squash interaction, how both the disease and the whitefly are being affected by climate change, and discuss current and novel ...
Nihal Oztolan‐Erol, Yusuf Sen, Melike Cokol‐Cakmak, Guler Demirbas‐Uzel, Stuart J. Lucas   +4 more
wiley   +1 more source

Berberine‐Pretreated Bone Marrow Mesenchymal Stem Cells Accelerate Skin Wound Healing in Rats With Burn Injuries

International Wound Journal, Volume 23, Issue 9, September 2026.
ABSTRACT Berberine (BBR) is a natural isoquinoline alkaloid with antibacterial, anti‐inflammatory and pro‐angiogenic properties. This study aimed to investigate the therapeutic efficacy and underlying mechanism of a conditioned medium (CM) derived from berberine‐preconditioned bone marrow‐derived mesenchymal stem cells (BMSCs‐BBR).
Jinglei Tan, Caiqiang Chen
wiley   +1 more source

Interactional Endocytosis and Transmembrane Transport Promote Cellular Internalization of Nano‐Delivered RNA Drugs for Efficient Control of Crop Diseases

Plant Biotechnology Journal, Volume 24, Issue 9, Page 5152-5171, September 2026.
ABSTRACT Botrytis cinerea is a widespread plant pathogenic ascomycete that causes grey mould in over 1400 species and impacts global crop yields. Double‐stranded RNA (dsRNA)‐induced gene silencing is a promising technology for pest control, but efficient delivery remains a major challenge.
Mei Guan, Chao Xie, Yang Xue, Juan Lu, Qinhong Jiang, Meizhen Yin, Shuo Yan, Jie Shen   +7 more
wiley   +1 more source

Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 7, July 2026.
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen, Tao‐Tao Shi, Dan‐Yang Hu, Xiao‐Na Su, Jian‐Xiang Jin, Mao‐Song Chen, Hao Wang, Wei Chen   +7 more
wiley   +1 more source

Lanzhou Lily (Lilium davidii var. unicolor) Extract Alleviates Chronic Stress–Induced Mood Disturbances by Suppressing Neuroinflammation and Modulating the Gut‐Brain Axis in Mice

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Lanzhou lily extract (LLE) alleviates chronic restraint stress–induced mood disturbances by reducing central inflammation, improving intestinal barrier integrity, attenuating systemic inflammation, and ultimately restoring gut–brain axis homeostasis in mice.
Ziyi An, Yuanyuan Xin, Yongfei Wang, Ting Wang, Junqiang Niu, Xiaogang Hu, Xiangkai Li, Weilin Jin   +7 more
wiley   +1 more source

Advances in Research on the Anti‐Tuberculosis Effects of Active Components in Chinese Herbal Medicine

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
This review summarizes how active constituents derived from Chinese herbal medicine exert anti‐tuberculosis (TB) effects via immunomodulation, direct inhibition of pathogens, and antioxidant activity. This synergistic, multi‐pathway mechanism highlights their potential as promising therapeutic candidates and adjunctive treatments against drug‐resistant
Qianqian Zhang, Siqi Lin, Juan Liu, Huani Wu, Xiaodan Lin, Jiawen He, Qiaoyu Yang, Jiang Pi, Fen Yang   +8 more
wiley   +1 more source

Phytotherapeutic Regulation of Matrix Metalloproteinases in Diabetic Foot Ulcer: Molecular Mechanisms and Wound Healing Perspectives

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Chronic inflammation in diabetic foot ulcers elevates MMP activity and suppresses TIMP and growth factor signaling, impairing tissue repair. Phytochemicals modulate NF‐κB/MAPK pathways and enhance Nrf2–TIMP expression, restoring MMP/TIMP balance, promoting collagen deposition, angiogenesis, and re‐epithelialization, leading to effective wound healing ...
Vishnu Priyan Elaiyaraja, Eswara Rajagopal, Subhikssha Babu, Balaji Sadhasivam   +3 more
wiley   +1 more source