Results 11 to 20 of about 4,598 (207)
Total Synthesis of Matrine Alkaloids [PDF]
Journal of the American Chemical Society, 2022 The total synthesis of three diastereomeric matrine natural products is reported. The eight-step synthesis commences with simple acyclic precursors, forms all four rings of the tetracyclic natural product framework and forges ten of the twenty covalent ...
Nicholas , Magann +4 more
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Molecular rotation spectrum of tetracyclic quinolizidines: Observation of trans-Matrine and the elusive cis-Matrine [PDF]
The Journal of Organic Chemistry, 2021 Producción CientíficaWe characterized the bis-quinolizidine tetracyclic alkaloid (5S, 6S, 7R, 11R)-matrine in a supersonic jet expansion, using chirped-pulsed broadband microwave spectroscopy.
Juanes San José, Marcos +4 more
core +5 more sources
Molecular Oncology, 2018 Matrine is a natural compound extracted from the herb Sophora flavescens Ait which is widely used in traditional Chinese medicine for treating various diseases. Recently, matrine was reported to have antitumor effects against a variety of cancers without
Young‐ra Cho +10 more
doaj +2 more sources
Frontiers in Cell and Developmental Biology, 2022 Hepatocellular carcinoma (HCC) is a complex issue in cancer treatment in the world at present. Matrine is the main active ingredient isolated from Sophora flavescens air and possesses excellent antitumor effects in HCC.
Kexin Wang +13 more
doaj +2 more sources
Matrine Mediates Inflammatory Response via Gut Microbiota in TNBS-Induced Murine Colitis [PDF]
Frontiers in Physiology, 2019 This study mainly investigated the effect of matrine on TNBS-induced intestinal inflammation in mice. TNBS treatment caused colonic injury and gut inflammation.
Peiyuan Li +5 more
doaj +2 more sources
Agronomy, 2023 Matrine is an efficient, low-toxicity, and environmentally friendly botanical pesticide; however, it is mainly applied as a soluble concentrate (SL) with a limited utilization rate that is unsuitable for ultra-low-volume spraying and unmanned aerial ...
Meng Li +5 more
doaj +2 more sources
Pharmaceutical Science AdvancesMatrine is the main component extracted from legumes and has extensive anti-cancer effects; however, its molecular mechanism is unclear. In our study, we found that matrine induced vacuolation in leukemia cells is closely related to cell proliferation ...
Fanfan Yang +5 more
doaj +2 more sources
Synthesis of Halopyrazole Matrine Derivatives and Their Insecticidal and Fungicidal Activities
Molecules, 2022 Matrine is a traditional botanical pesticide with a broad-spectrum biological activity that is widely applied in agriculture. Halopyrazole groups are successfully introduced to the C13 of matrine to synthesize eight new derivatives with a yield of 78–87%.
Xingan Cheng +9 more
doaj +2 more sources
Cancer Medicine, 2018 Background Matrine, a traditional Chinese medicine, has recently been shown to have antitumor properties in diverse cancer cells. Here, we explored the effect of matrine on human glioblastoma multiforme (GBM) cells.
Wenjing Zhou +11 more
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Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1α [PDF]
Frontiers in Pharmacology, 2019 The Warburg effect is a peculiar feature of cancer’s metabolism, which is an attractive therapeutic target that could aim tumor cells while sparing normal tissue.
Xiaoting Hong +15 more
doaj +2 more sources