Results 111 to 120 of about 5,505 (195)

Multi-Platform Proteomic Analysis of Alzheimer’s Disease Cerebrospinal Fluid and Plasma Reveals Network Biomarkers Associated with Proteostasis and the Matrisome [PDF]

, 2022
Eric B. Dammer, Lingyan Ping, Duc M. Duong, Erica Modeste, Nicholas T. Seyfried, James J. Lah, Allan I. Levey, Erik C. B. Johnson   +7 more
openalex   +1 more source

Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma

Scientific Reports, 2018
Increasing evidence demonstrates an important role for the extracellular matrix (ECM) in breast cancer progression. Collagen type I, a core constituent of the fibrous ECM, undergoes a significant set of changes that accompany tumor progression, termed ...
Lucas A. Tomko, Ryan C. Hill, Alexander Barrett, Joseph M. Szulczewski, Matthew W. Conklin, Kevin W. Eliceiri, Patricia J. Keely, Kirk C. Hansen, Suzanne M. Ponik   +8 more
doaj   +1 more source

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. [PDF]

, 2019
Gene copy number alterations, tumor cell stemness, and the development of platinum chemotherapy resistance contribute to high-grade serous ovarian cancer (HGSOC) recurrence.
Anderson, Kristen, Barrie, Allison M, Bean, Lisa M, Chen, Xiao Lei, Connolly, Denise C, Cordasco, Edward A, Diaz Osterman, Carlos J, Fisch, Kathleen M, Fu, Guo, Győrffy, Balázs, Heino, Jyrki, Jean, Christine, Jiang, Shulin, Kleinschmidt, Elizabeth G, Kolev, Vihren N, Li, Jian, Mark, Adam M, McHale, Michael T, Molinolo, Alfredo, Ojalill, Marjaana, Ozmadenci, Duygu, Pachter, Jonathan A, Rappu, Pekka, Schlaepfer, David D, Stupack, Dwayne G, Sulzmaier, Florian J, Tancioni, Isabelle, Taylor, Kristin N, Uryu, Sean, Weaver, David T, Xu, Guorong   +30 more
core   +1 more source

The alternative matrisome: Alternative splicing of ECM proteins in development, homeostasis and tumor progression

, 2022
Zeinab Rekad, Valerio Izzi, Rijuta Lamba, Delphine Ciais, Ellen Van Obberghen‐Schilling   +4 more
openalex   +2 more sources

Fibroblast subtypes define a metastatic matrisome in breast cancer [PDF]

, 2020
Heather M. Brechbuhl, Alexander Barrett, Etana Kopin, Jaime Hagen, Amy Han, Austin E. Gillen, Jessica Finlay-Schultz, Diana M. Cittelly, Philip Owens, Kathryn B. Horwitz, Carol A. Sartorius, Kirk C. Hansen, Peter Kabos   +12 more
openalex   +1 more source

Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. [PDF]

, 2019
Progressive organ fibrosis accounts for one-third of all deaths worldwide, yet preclinical models that mimic the complex, progressive nature of the disease are lacking, and hence, there are no curative therapies. Progressive fibrosis across organs shares
Ahadome, Sarah D, Aros, Cody J, Bhatt, Kush V, Chung, Katherine, Clark, Amander T, Damoiseaux, Robert, Darmawan, Kelly F, Durra, Abdo, Gomperts, Brigitte N, Graeber, Thomas G, Karumbayaram, Saravanan, Manze, Chase C, Mehrabi, Mehrsa, Minasyan, Aspram, Paul, Manash K, Rickabaugh, Tammy M, Sandlin, Jenna M, Shia, David W, Vijayaraj, Preethi, Wallace, W Dean, Wilkinson, Dan C, Yan, Weihong   +21 more
core   +1 more source

The role of the synovial microenvironment in Rheumatoid Arthritis [PDF]

Rheumatoid Arthritis (RA) remains plagued by poor treatment responses and a lack of curative solutions despite a dense armamentarium. A deeper investigation into the tissue biology of the RA synovium, including its cells but also the remodelled ...
Richard, Jean-Baptiste
core   +2 more sources

Data from Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma

, 2023
Chenxi Tian, Daniel Öhlund, Steffen Rickelt, Tommy Lidström, Ying Huang, Liang Hao, Renee T. Zhao, Oskar Franklin, Sangeeta N. Bhatia, David A. Tuveson, Richard O. Hynes   +10 more
openalex   +1 more source

Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer [PDF]

, 2021
Robin M. Delaine‐Smith, Eleni Maniati, Beatrice Malacrida, Sam Nichols, Reza Roozitalab, Roanne R. Jones, Laura S.M. Lecker, Oliver M.T. Pearce, Martin M. Knight, Frances R. Balkwill   +9 more
openalex   +1 more source

Matrisome, innervation and oxidative metabolism affected in older compared with younger males with similar physical activity [PDF]

, 2021
Bart Lagerwaard, Arie G. Nieuwenhuizen, Annelies Bunschoten, Vincent C. J. de Boer, Jaap Keijer   +4 more
openalex   +1 more source