Multi-Platform Proteomic Analysis of Alzheimer’s Disease Cerebrospinal Fluid and Plasma Reveals Network Biomarkers Associated with Proteostasis and the Matrisome [PDF]
Eric B. Dammer +7 more
openalex +1 more source
Increasing evidence demonstrates an important role for the extracellular matrix (ECM) in breast cancer progression. Collagen type I, a core constituent of the fibrous ECM, undergoes a significant set of changes that accompany tumor progression, termed ...
Lucas A. Tomko +8 more
doaj +1 more source
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. [PDF]
Gene copy number alterations, tumor cell stemness, and the development of platinum chemotherapy resistance contribute to high-grade serous ovarian cancer (HGSOC) recurrence.
Anderson, Kristen +30 more
core +1 more source
Fibroblast subtypes define a metastatic matrisome in breast cancer [PDF]
Heather M. Brechbuhl +12 more
openalex +1 more source
Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. [PDF]
Progressive organ fibrosis accounts for one-third of all deaths worldwide, yet preclinical models that mimic the complex, progressive nature of the disease are lacking, and hence, there are no curative therapies. Progressive fibrosis across organs shares
Ahadome, Sarah D +21 more
core +1 more source
The role of the synovial microenvironment in Rheumatoid Arthritis [PDF]
Rheumatoid Arthritis (RA) remains plagued by poor treatment responses and a lack of curative solutions despite a dense armamentarium. A deeper investigation into the tissue biology of the RA synovium, including its cells but also the remodelled ...
Richard, Jean-Baptiste
core +2 more sources
Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer [PDF]
Robin M. Delaine‐Smith +9 more
openalex +1 more source
Matrisome, innervation and oxidative metabolism affected in older compared with younger males with similar physical activity [PDF]
Bart Lagerwaard +4 more
openalex +1 more source

