NELL-1 regulates the matrisome to alter osteosarcoma disease progression [PDF]
Qizhi Qin +8 more
openalex +1 more source
Cell-selective labeling using amino acid precursors for proteomic studies of multicellular environments. [PDF]
We report a technique to selectively and continuously label the proteomes of individual cell types in coculture, named cell type-specific labeling using amino acid precursors (CTAP).
A Naba +42 more
core +1 more source
The extracellular matrix component perlecan/HSPG2 regulates radioresistance in prostate cancer cells
Radiotherapy of prostate cancer (PC) can lead to the acquisition of radioresistance through molecular mechanisms that involve, in part, cell adhesion-mediated signaling.
Ivana Samaržija +18 more
doaj +1 more source
The fabrication of a cellularized, multilayered 3D printed cylindrical model comprising hybrid bioinks inspired by the natural extracellular environment as an approach to artery mimetics, is presented. Using embedded bioprinting, interlayer crosslinking of self‐supporting concentric cylinders is achieved.
Uxue Aizarna‐Lopetegui +7 more
wiley +1 more source
MicroRNAs Associated with Shoulder Tendon Matrisome Disorganization in Glenohumeral Arthritis
The extracellular matrix (ECM) provides core support which is essential for the cell and tissue architectural development. The role of ECM in many pathological conditions has been well established and ECM-related abnormalities leading to serious consequences have been identified.
Finosh G. Thankam +4 more
openaire +4 more sources
During early avian development, primordial germ cells (PGC) are highly migratory, moving from the central area pellucida of the blastoderm to the anterior extra-embryonic germinal crescent.
David J. Huss +14 more
doaj +1 more source
Rethinking Matrigel: The Complex Journey to Matrix Alternatives in Organoid Culture
Matrigel remains the most widely used scaffold in organoid and 3D culture despite its murine origin, variability, and translational limitations. This review discusses the barriers to replacing Matrigel with xeno‐free alternatives and introduces practical tools, including a matrix selection checklist and scaffold assessment criteria, to guide the ...
Lisa Wolff, Sven Hendrix
wiley +1 more source
Proteomic analysis of decellularized mice liver and kidney extracellular matrices
Background The extracellular matrix (ECM) is a three-dimensional network of proteins that encases and supports cells within a tissue and promotes physiological and pathological cellular differentiation and functionality.
Anna-Maria Diedrich +14 more
doaj +1 more source
Use of Conditioned Extracellular Matrix as a Tissue-engineered Tumor Matrisome for Prostate Cancer and Melanoma Immunotherapy [PDF]
Mark A. Suckow, Michael C. Hiles
openalex +1 more source
Emerging tumor spheroids technologies for 3D in vitro cancer modeling [PDF]
"Article in Press, Available online 31 October 2017" ; "S0163-7258(17)30268-1"Cancer is a leading cause of mortality and morbidity worldwide. Around 90% of deaths are caused by metastasis and just 10% by primary tumor.
Alemany-Ribes +133 more
core +1 more source

