Results 111 to 120 of about 5,938 (234)
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
Cell, 2022 J. Tcw +20 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2019 During early avian development, primordial germ cells (PGC) are highly migratory, moving from the central area pellucida of the blastoderm to the anterior extra-embryonic germinal crescent.
David J. Huss +14 more
doaj +1 more source
Molecular Oncology, Volume 19, Issue 9, Page 2594-2618, September 2025.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Advanced Science, Volume 12, Issue 36, September 25, 2025.The present study identified the key protein ORM1 through the proteomic analysis of synovial fluid samples from patients with temporomandibular joint osteoarthritis (TMJOA), and demonstrated the important role of ORM1 in maintaining cartilage homeostasis via the suppression of VIM/MAPK/MMP signalling.
Dahe Zhang +5 more
wiley +1 more source
Proteomic analysis of decellularized mice liver and kidney extracellular matrices
Journal of Biological EngineeringBackground The extracellular matrix (ECM) is a three-dimensional network of proteins that encases and supports cells within a tissue and promotes physiological and pathological cellular differentiation and functionality.
Anna-Maria Diedrich +14 more
doaj +1 more source
Rare loss-of-function variants in matrisome genes are enriched in Ebstein’s anomaly
HGG AdvancesSummary: Ebstein’s anomaly, a rare congenital heart disease, is distinguished by the failure of embryological delamination of the tricuspid valve leaflets from the underlying primitive right ventricle myocardium. Gaining insight into the genetic basis of
Zhou Zhou +7 more
doaj +1 more source
Differential Gene Expression of Fresh Tissue and Patient-Derived Explants’ Matricellular Proteins Augment Inflammatory Breast Cancer Metastasis: The Possible Role of IL-6 and MCP-1 [PDF]
, 2023 BACKGROUND: Matricellular proteins comprising matrisome and adhesome are responsible for structure integrity and interactions between cells in the tumour microenvironment of breast cancer.
El-Sayed, Shrouk Khalaf +7 more
core +1 more source
Long non-coding RNA H19 regulates matrisome signature and impacts cell behavior on MSC-engineered extracellular matrices [PDF]
, 2022 Sara Reis Moura +8 more
openalex +1 more source
Deciphering Cell-Type and Temporal-Specific Matrisome Expression Signatures in Human Cortical Development and Neurodevelopmental Disorders via scRNA-Seq Meta-Analysis [PDF]
Gim DH +5 more
europepmc +2 more sources
Frontiers in Cellular NeuroscienceThe maturation of brain microvascular endothelial cells leads to the formation of a tightly sealed monolayer, known as the blood–brain barrier (BBB). The BBB damage is associated with the pathogenesis of age-related neurodegenerative diseases including ...
Yasuteru Inoue +11 more
doaj +1 more source