Results 41 to 50 of about 322,605 (305)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Label-free analytic histology of carotid atherosclerosis by mid-infrared optoacoustic microscopy
Photoacoustics, 2022 Background and aims: Analysis of atherosclerotic plaque composition is a vital tool for unraveling the pathological metabolic processes that contribute to plaque growth.
Mirjam Visscher +5 more
doaj +1 more source
Analytic Hierarchy approach for transport project appraisal an application to Korea [PDF]
, 1998 Transport evaluation methodology in Korea has remained largely unchanged even though the evolution of the transport planning process has changed in its nature and circumstances.
Lee , Sang Min
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
MathematicsInterdependent criteria play a crucial role in complex decision-making across various domains. Traditional methods often struggle to evaluate and prioritize criteria with intricate dependencies.
Jih-Jeng Huang, Chin-Yi Chen
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Analytic solution for a circular nano-inhomogeneity in a finite matrix
Nano Materials Science, 2019 The Gurtin-Murdoch model has found wide applications in analyzing the mechanical behaviors of nanocomposites with surface/interface effect. In the existing literature, the matrix is usually assumed to be infinite and the surface/interface effect is ...
Shuang Wang, Zengtao Chen, Cunfa Gao
doaj +1 more source
Results in Applied Mathematics, 2022 The present work is devoted to developing two numerical techniques based on fractional Bernstein polynomials, namely fractional Bernstein operational matrix method, to numerically solving a class of fractional integro-differential equations (FIDEs).
M.H.T. Alshbool +3 more
doaj +1 more source
Matrix analytic methods for computations in risk theory [PDF]
, 2019 The introduction of matrix analytic methods in risk theory has marked a significant progress in computations in risk theory. Matrix analytic methods have proven to be powerful computational tools for numerically analyzing complex risk models that ...
Kim, Sung Soo
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source