Results 91 to 100 of about 7,283,251 (294)

Confining iodide migration with quantified barrier for durable perovskite solar cells

Nature Communications
The migration of iodide ions out of the perovskite film degrades charge transport and electrode layers, reducing the long-term stability of perovskite solar cells.
Hongcai Tang, Yangzi Shen, Ge Yan, Liyuan Han, Qifeng Han   +4 more
doaj   +1 more source

Quivers from Matrix Factorizations

, 2010
We discuss how matrix factorizations offer a practical method of computing the quiver and associated superpotential for a hypersurface singularity. This method also yields explicit geometrical interpretations of D-branes (i.e., quiver representations) on
A. Bergman, A. Hanany, A. Kapustin, B. Feng, C. Beasley, C.I. Lazaroiu, D. Berenstein, D. Eisenbud, D.R. Morrison, David R. Morrison, E. Segal, G. Gonzalez-Sprinberg, H. Knörrer, I.R. Klebanov, J. Kollár, M. Aganagic, M. Auslander, M. Auslander, M. Kapranov, M. Van den Bergh, M.J. Bardzell, M.R. Douglas, N. Carqueville, N. Seiberg, P.S. Aspinwall, P.S. Aspinwall, P.S. Aspinwall, P.S. Aspinwall, Paul S. Aspinwall, S. Gubser, S. Katz   +30 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Synchronized crystallization in tin-lead perovskite solar cells

Nature Communications
Tin-lead halide perovskites with a bandgap near 1.2 electron-volt hold great promise for thin-film photovoltaics. However, the film quality of solution-processed Sn-Pb perovskites is compromised by the asynchronous crystallization behavior between Sn and
Yao Zhang, Chunyan Li, Haiyan Zhao, Zhongxun Yu, Xiaoan Tang, Jixiang Zhang, Zhenhua Chen, Jianrong Zeng, Peng Zhang, Liyuan Han, Han Chen   +10 more
doaj   +1 more source

The Evaluation Matrix [PDF]

, 2004
Evaluation is one of the most confusing topics in philanthropy -- in part because it embraces multiple definitions that are often jumbled together. Evaluation often refers to at least three different kinds of measures: monitoring measures that typically ...
Mark R. Kramer
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Abnormal grain growth in randomly-oriented fine grains in an Al–Mg–Sc–Zr alloy processed by laser-powder-bed-fusion

Materials Research Letters
In this work, we report a counter-intuitive activation of abnormal grain growth (AGG) in randomly-oriented fine grains (FGs) in an L-PBF Al–Mg–Sc–Zr alloy, which is unlikely from perspectives of curvature-driven grain growth, crystallographic texture or ...
Yanchi Chen, Xiang Chen, Han Chen, Yakai Xiao, Jing Dai, Yidan Chen, Yuchi Cui, Chengyi Dan, Zhe Chen, Xianfeng Li, Haowei Wang   +10 more
doaj   +1 more source