Results 81 to 90 of about 7,280,185 (293)

Matrix Models [PDF]

, 2019
Contains fulltext : 103494pre.pdf (Author’s version preprint ) (Open Access)
Jongejans, E., de Kroon, H.
openaire   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Natural graft tissues and synthetic biomaterials for periodontal and alveolar bone reconstructive applications: a review

Biomaterials Research, 2017
Periodontal disease is categorized by the destruction of periodontal tissues. Over the years, there have been several clinical techniques and material options that been investigated for periodontal defect repair/regeneration.
Zeeshan Sheikh, Nader Hamdan, Yuichi Ikeda, Marc Grynpas, Bernhard Ganss, Michael Glogauer   +5 more
doaj   +1 more source

Matrix showing the variations of pre - registration nursing programmes between Singapore and the four UK countries [PDF]

, 2014
The Singapore data is based on a Prof essor Sir Ron Cooke International Scholar ship Scheme, which may have changed since observation in July to Nov ember 2012 .
Loke, Jennifer
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Evaluating Matrix Circuits

, 2015
The circuit evaluation problem (also known as the compressed word problem) for finitely generated linear groups is studied. The best upper bound for this problem is $\mathsf{coRP}$, which is shown by a reduction to polynomial identity testing. Conversely,
C Àlvarez, DK Biss, E Allender, E Allender, E Allender, L Auslander, M Beaudry, M Lohrey, M Lohrey, M Lohrey, OH Ibarra, R Swan, RJ Lipton, S Waack, SA Cook, V Kabanets, W Hesse   +16 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Flame-Synthesis of Carbon Nanotube Forests on Metal Mesh Structure: Dependence, Morphology, and Application

Nanomaterials, 2019
Multi-walled carbon nanotubes (MWCNTs) in the form of “forests” were synthesized directly on the surface of stainless steel (SS) mesh from ethanol flame volume.
Xuhai Xiong, Pu Zhao, Rong Ren, Xu Cui, Shude Ji   +4 more
doaj   +1 more source

Exploiting the structure effectively and efficiently in low rank matrix recovery

, 2018
Low rank model arises from a wide range of applications, including machine learning, signal processing, computer algebra, computer vision, and imaging science.
Absil, Agarwal, Ahmed, Alter, Amelunxen, Beck, Blanchard, Blumensath, Boumal, Boyd, Bunk, Cai, Cai, Cai, Cai, Cai, Cai, Candes, Candes, Candes, Candes, Candes, Candès, Candès, Candès, Candès, Carmon, Chandrasekaran, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Combettes, Davenport, Davenport, Ding, Donoho, Fazel, Ge, Ge, Ge, Goldberg, Gross, Hardt, Harrison, Huang, Jaggi, Jain, Jain, Ji, Jin, Keshavan, Kim, Kliesch, Koltchinskii, Krim, Kueng, Lanman, Li, Li, Lin, Ling, Ling, Liu, Liu, Lustig, Ma, Miao, Mishra, Mishra, Mishra, Mobahi, Mu, Negahban, Netrapalli, Ngo, Potter, Qu, Recht, Recht, Schermelleh, Srebro, Strohmer, Sun, Sun, Tanner, Tanner, Tao, Tharrault, Toh, Toh, Tomasi, Tu, Vandereycken, Wang, Wei, Wei, Wei, Wen, WenHuang, Xu, Yi, Zhang, Zhang, Zheng   +109 more
core   +2 more sources