Results 51 to 60 of about 3,837,712 (252)

Importance of the linker region in matrix metalloproteinase-1 domain interactions† [PDF]

open access: yesRSC Advances, 2016
Collagenolysis is catalyzed by enzymes from the matrix metalloproteinase (MMP) family, where one of the most studied is MMP-1. The X-ray crystallographic structure of MMP-1 complexed with a collagen-model triple-helical peptide (THP) provided important ...
Warispreet Singh   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Cross-Domain Latent Factors Sharing via Implicit Matrix Factorization [PDF]

open access: yes
Data sparsity has been one of the long-standing problems for recommender systems. One of the solutions to mitigate this issue is to exploit knowledge available in other source domains.
Vakhrushev, Anton   +4 more
core   +1 more source

On Some New Rhaly Sequence Spaces and Rhaly Sections in BK-Space

open access: yesCommunications in Advanced Mathematical Sciences
In this paper, we introduce some new sequence spaces and sectional subspaces related to the Rhaly matrix and BK spaces. Furthermore, we investigate their relations and identities among these subspaces and duals.
Abdulaziz Daş, Bilal Altay
doaj   +1 more source

On matrix Reinhardt domains

open access: yesMathematische Annalen, 1990
Let D be a domain in the space \({\mathbb{C}}^ n[m\times m]={\mathbb{C}}^{nm^ 2}\) of n matrix variables with \(m\times m\) entries, i.e. the points of D are given by n-tuples \(Z=(Z_ 1,...,Z_ n)\) where \(Z_ i\in {\mathbb{C}}[m\times m]\) are \(m\times m\) matrices with complex entries, \(i=1,...,n\). D is called a matrix Reinhardt domain, if \((Z_ 1,.
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Spatial frequency domain Mueller matrix imaging

open access: yesPolarized Light and Optical Angular Momentum for Biomedical Diagnostics, 2021
SignificanceMueller matrix polarimetry (MMP) and spatial frequency domain imaging (SFDI) are wide-field optical imaging modalities that differentiate tissue primarily by structure alignment and photon transport coefficient, respectively. Because these effects can be related, combining MMP and SFDI may enhance tissue differentiation beyond the ...
Joseph Chue-Sang   +3 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Scatter Matrix Based Domain Adaptation for Bi-Temporal Polarimetric SAR Images

open access: yesRemote Sensing, 2020
Time series analysis (TSA) based on multi-temporal polarimetric synthetic aperture radar (PolSAR) images can deeply mine the scattering characteristics of objects in different stages and improve the interpretation effect, or help to extract the range of ...
Weidong Sun   +6 more
doaj   +1 more source

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