Results 61 to 70 of about 3,837,712 (252)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

A new regular infinite matrix defined by Jordan totient function and its matrix domain in l(p) [PDF]

open access: yes, 2020
In this paper, we first define a new regular matrix by using the arithmetic function called Jordan totient function and study the matrix domain of this newly introduced matrix in the Banach space l(p).
Merve İlkhan   +5 more
core   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

The Complex Domain Matrix of Ditransitive Constructions

open access: yes, 2022
This study focuses on the semantics of ditransitive constructions. Its main aim is to show that the semantics of this type of construction is made up of elements belonging to different conceptual domains. In order to fully analyze the complexity inherent
Unternbäumen, Enrique Huelva
core   +1 more source

Multiple functions of the von Willebrand Factor A domain in matrilins: secretion, assembly, and proteolysis

open access: yesJournal of Orthopaedic Surgery and Research, 2008
The von Willebrand Factor A (vWF A) domain is one of the most widely distributed structural modules in cell-matrix adhesive molecules such as intergrins and extracellular matrix proteins.
Kanbe Katsuaki   +4 more
doaj   +1 more source

A Hilbert Transform for Matrix Functions on Fractal Domains [PDF]

open access: yesComplex Analysis and Operator Theory, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Abreu-Blaya, R.   +4 more
openaire   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Almost convergent sequence spaces derived by the domain of quadruple band matrix

open access: yesAnnales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2020
In this work, we construct the sequence spaces f(Q(r,s,t,u)), f0(Q(r,s,t,u)) and fs(Q(r,s,t,u)), where Q(r,s,t,u) is quadruple band matrix which generalizes the matrices Δ3, B(r,s,t), Δ2, B(r,s) and Δ, where Δ3, B(r,s,t), Δ2, B(r,s) and Δ are called ...
Mustafa Cemil Bişgin
doaj  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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