Results 81 to 90 of about 7,157,448 (338)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
General solution of the Poisson equation for Quasi-Birth-and-Death processes
, 2016 We consider the Poisson equation $(I-P)\boldsymbol{u}=\boldsymbol{g}$, where $P$ is the transition matrix of a Quasi-Birth-and-Death (QBD) process with infinitely many levels, $\bm g$ is a given infinite dimensional vector and $\bm u$ is the unknown. Our
Bini, Dario A. +3 more
core +1 more source
, 2021 Pongsakorn Sunthrayuth +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Matrix solutions of a noncommutative KP equation and a noncommutative mKP equation
, 2009 Matrix solutions of a noncommutative KP and a noncommutative mKP equation which can be expressed as quasideterminants are discussed.
A. Dimakis +20 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Positive Definite Solutions of the Matrix Equation
, 2015 We investigate the nonlinear matrix equation , where is a positive integer and . We establish necessary and sufficient conditions for the existence of positive definite solutions of this equation.
Asmaa M. Al-Dubiban
semanticscholar +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
FEBS Open Bio, EarlyView.A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
Poles in the $S$-Matrix of Relativistic Chern-Simons Matter theories from Quantum Mechanics
, 2015 An all orders formula for the $S$-matrix for 2 $\rightarrow$ 2 scattering in large N Chern-Simons theory coupled to a fundamental scalar has recently been conjectured.
Dandekar, Yogesh +2 more
core +1 more source
Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
FEBS Open Bio, EarlyView.Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source