Results 41 to 50 of about 1,983,602 (251)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Adaptive Kernel Graph Nonnegative Matrix Factorization

open access: yesInformation, 2023
Nonnegative matrix factorization (NMF) is an efficient method for feature learning in the field of machine learning and data mining. To investigate the nonlinear characteristics of datasets, kernel-method-based NMF (KNMF) and its graph-regularized ...
Rui-Yu Li, Yu Guo, Bin Zhang
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The General Inner-Outer Factorization Problem for Discrete-Time Systems [PDF]

open access: yes, 1999
In this paper we give a theoretical and a computational solution to the most general inner-outer factorization problem formulated for a discrete-time system G.
A. Varga   +3 more
core   +1 more source

Banach Spaces of Analytic Vector-valued Functions [PDF]

open access: yes, 2007
The main theme of the thesis is the study of continuity and approximation problems, involving matrix-valued and vector-valued Hardy spaces on the unit disc ID and its boundary T in the complex plane.
Barclay, Steven John
core   +5 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Computation of Inner-Outer Factorizations of Rational Matrices [PDF]

open access: yes, 1997
In this paper we propose a new numerically reliable computational approach to determine the inner-outer factorization of a rational transfer matrix G of a linear descriptor system.
A. Varga, Andras Varga, Varga, A.
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Matrix Factorization With Rating Completion: An Enhanced SVD Model for Collaborative Filtering Recommender Systems

open access: yesIEEE Access, 2017
Collaborative filtering algorithms, such as matrix factorization techniques, are recently gaining momentum due to their promising performance on recommender systems. However, most collaborative filtering algorithms suffer from data sparsity.
Xin Guan, Chang-Tsun Li, Yu Guan
doaj   +1 more source

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