Results 251 to 260 of about 19,663,610 (303)

Atrial cardiomyopathy

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala   +1 more
wiley   +1 more source

Increasing of matrix metalloproteinase 3 in bovine endometritis

Theriogenology, 2021
Matrix metalloproteinase 3 (MMP3), a key member of the MMPs family, is involved in the modulation of endometrial inflammation and innate immunity. However, the role of MMP3 in bovine endometritis remains unknown. To investigate the role of MMP3 in bovine endometritis, endometrial MMP3 expression were determined in uterine biopsies from twenty 40-60 ...
Shidong Zhang   +2 more
openaire   +2 more sources

Matrix metalloproteinase-3 serum levels in schizophrenic patients

International Journal of Psychiatry in Clinical Practice, 2022
It has been reported that matrix metalloproteinase, MMP-3 may play a significant role in the pathophysiology of mental disorders. However, there are no data on the level of MMP-3 in people suffering from schizophrenia, or its influence on the mental state of these people. The aim of this study was to investigate the effect of an antipsychotic treatment
Michal Ordak   +6 more
openaire   +2 more sources

The importance of matrix metalloproteinase-3 in respiratory disorders

Expert Review of Respiratory Medicine, 2014
The matrix metalloproteinases (MMPs) encompass a family of zinc-dependent endopeptidases that are secreted into the extracellular environment or remain bound to the cell surface. While MMPs were initially identified based on their ability to degrade collagen and other components of the extracellular matrix, recent studies indicate that their non ...
Cory M, Yamashita   +3 more
openaire   +2 more sources

Matrix metalloproteinase‐3 and intracranial arterial dolichoectasia

Annals of Neurology, 2010
AbstractObjectiveIntracranial arterial dolichoectasia (IADE), also called dilatative arteriopathy of the brain, is defined as an increase in length and diameter of intracranial arteries. Abdominal aortic aneurysm and ectasia of coronary arteries have been reported in association with IADE. In both conditions, a dysfunction of matrix metalloproteinases (
Fernando, Pico   +9 more
openaire   +2 more sources

Serum matrix metalloproteinase-3 in systemic sclerosis

Archives of Dermatological Research, 2004
To determine the serum levels of matrix metalloproteinase-3 (MMP-3) in patients with systemic sclerosis (SSc) and investigate their clinical significance in this disease, serum samples from 83 patients with SSc and 30 healthy volunteers were examined by a specific enzyme-linked immunosorbent assay (ELISA).
Masatoshi, Jinnin   +5 more
openaire   +2 more sources

Structure of matrix metalloproteinase-3 with a platinum-based inhibitor

Chemical Communications, 2013
An X-ray investigation has been performed with the aim of characterizing the binding sites of a platinum-based inhibitor (K[PtCl3(DMSO)]) of matrix metalloproteinase-3 (stromelysin-1). The platinum complex targets His224 in the S1' specificity loop, representing the first step in the selective inhibition process (PDB ID code 4JA1).
Belviso Benny Danilo   +5 more
openaire   +7 more sources

Spontaneous metastasis in matrix metalloproteinase 3‐deficient mice

Molecular Carcinogenesis, 2008
AbstractMatrix metalloproteinases (MMPs) have been linked to the metastatic potential of tumor cells due to their ability to degrade the extracellular matrix. MMP‐3 (stromelysin‐1) is upregulated in a wide variety of human tumors. We used the MMTV‐PyMT breast cancer model to determine if MMP‐3 is involved in tumorigenesis and metastatic growth. In this
Juncker-Jensen, Anna   +4 more
openaire   +3 more sources

Matrix Metalloproteinase-3 Differences in Oral and Skin Fibroblasts

Journal of Dental Research, 2007
While skin wounds heal by scarring, wounds of oral mucosa show privileged healing with minimal scar formation. Our hypothesis was that phenotypic differences between oral and skin fibroblasts underlie these differences in healing. The aims of this study were to compare MMP-3 expression by oral and skin fibroblasts and investigate a role for MMP-3 in ...
S T W, McKeown   +5 more
openaire   +2 more sources

Serum levels of matrix metalloproteinase‐3 in undifferentiated spondyloarthropathy

Scandinavian Journal of Rheumatology, 2007
Spondyloarthropathy (SpA) is a family of chronic arthritis, characterized by inflammatory back pain, peripheral arthritis, and enthesitis [1].
C-H, Chen   +5 more
openaire   +2 more sources

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