Matrix metalloproteinase-3 - Open Access .click

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Matrix metalloproteinase-3 contributes to vulnerability of the nigral dopaminergic neurons

Neurochemistry International, 2010
Dopamine(DA)rgic neurons are particularly vulnerable due to the presence of oxidative stress-inducing molecules such as DA, tetrahydrobiopterin, iron and tyrosine hydroxylase (TH). We have recently observed that matrix metalloproteinase-3 (MMP-3) is involved in degeneration of DArgic neurons. In the present study, we sought to explore the role of MMP-3
Sung Tae, Kim +7 more
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Gene polymorphism of matrix metalloproteinases 3 and 9 in breast cancer

Gene Reports, 2016
Background Genetic factors have a considerable influence on development and progress of malignancy. Matrix metallo‐proteinases (MMPs) are a group of proteolytic enzymes which are proved to be involved in pathogenesis of breast cancer.
Naglaa Raafat Abdraboh Soliman, Fatehia Ali Bayoumi +1 more
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Serum matrix metalloproteinase-3 levels are elevated in myasthenia gravis

Journal of Neuroimmunology, 2008
MMP-3 is capable of degrading a variety of proteins, including agrin, which plays a critical role in neuromuscular signalling by controlling acetylcholine receptor clustering. The degradation of agrin by MMP-3 may disrupt the neuromuscular junction leading to a failure of neuromuscular transmission and muscle weakness.
Fredrik R, Romi, Nils Erik, Gilhus, Steven P, Luckman +2 more
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AB1053 MATRIX METALLOPROTEINASE-3: A BIOMARKER OF SPONDYLOARTHRITIS