Results 231 to 240 of about 386,755 (358)

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

[Expression of Concern] Halofuginone induces the apoptosis of breast cancer cells and inhibits migration via downregulation of matrix metalloproteinase‑9. [PDF]

Int J Oncol
Jin ML, Park SY, Kim YH, Park G, Lee SJ.
europepmc   +1 more source

Effects of Matrix Metalloproteinase-9 Gene Knock-Out on the Proteolysis of Blood–Brain Barrier and White Matter Components after Cerebral Ischemia

Journal of Neuroscience, 2001
M. Asahi, Xiaoying Wang, Tatsuro Mori, T. Sumii, Jae‐Chang Jung, M. A. Moskowitz, M. E. Fini, E. Lo   +7 more
semanticscholar   +1 more source

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

Advanced Science, EarlyView.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng, Yuxin Bai, Zhibo Liu, Zinan Zhao, Yiming Kong, Yao Xu, Qi Jia, Rongrong Zhu, Yong Hu   +8 more
wiley   +1 more source

Matrix metalloproteinase‑9 in hemorrhagic transformation after acute ischemic stroke (Review). [PDF]

Mol Med Rep
Guo P, Li H, Zhang X, Liu Y, Xue S, Yong VW, Xue M.   +6 more
europepmc   +1 more source

Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro

Advanced Science, EarlyView.
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner, Petra B. Welzel, Maximilian Fusenig, Linda Sturm, Dagmar Pette, Wolfgang Wagermaier, Claudia Fischbach, Peter Fratzl, Carsten Werner   +8 more
wiley   +1 more source

Matrix Metalloproteinase-9 as a Biomarker for Diagnosis and Monitor Disease Progression in Psoriatic Arthritis. [PDF]

Mediterr J Rheumatol
Prisila T, Ong PS, Said MSM, Wahab AA.
europepmc   +1 more source

Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels.

American Journal of Physiology - Lung cellular and Molecular Physiology, 2014
Tetsu Kobayashi, Huijung Kim, Xiangde Liu, H. Sugiura, T. Kohyama, Q. Fang, F. Wen, S. Abe, Xingqi Wang, J. Atkinson, J. Shipley, R. Senior, S. Rennard   +12 more
semanticscholar   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

Matrix Metalloproteinase-9 and Postoperative Outcomes in Carotid Endarterectomy: A Systematic Review. [PDF]

J Clin Med
Gonçalves-Silva J, Fragão-Marques M, Ribeiro H, Sá SI, Rocha-Neves J.   +4 more
europepmc   +1 more source