Results 81 to 90 of about 233,826 (312)

Evaluation of the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population [PDF]

, 2006
Background Bowel cancer is common and is a major cause of death. Meta-analysis of randomised controlled trials estimates that screening for colorectal cancer using faecal occult blood (FOB) test reduces mortality from colorectal cancer by 16%.
Redman, VD, Michael JO Wakelam, Colbourne, L, Janet A Dunn, Val D Redman, Lynne Colbourne, Dunn, Janet, Martin, A, Martin Ashley, Wilson, S, Wakelam, Michael, Ismail, T, Hobbs Richard FD, Wakelam, Michael J.O., Sue Wilson, Hobbs, RFD, Martin, Ashley, Wilson, Sue, Dr, Redman, Valerie, Colbourne Lynne, Wakelam, MJ, Redman, Val. D., Colbourne, Lynne, Ryan, Angela V., Wilson Sue, Angela V Ryan, Ryan, AV, Tariq Ismail, Fiona Patrick, Ashley Martin, Richard FD Hobbs, Ryan Angela V, Patrick, Fiona, Patrick, F, Ismail, Tariq, Ismail Tariq, Dunn, Janet A., Wilson, Sue, Redman Val D, Ryan, Angela, Dunn Janet A, Wakelam, MJO, Hobbs, RF, Dunn, JA, Hobbs, Richard F. D., Patrick Fiona, Wakelam Michael JO   +46 more
core   +1 more source

The Relationship between Matrix Metalloproteinase Gene Polymorphisms and Tumor Type, Tumor Size, and Metastasis in Women with Breast Cancer in Central Iran

Middle East Journal of Cancer, 2018
Background: Matrix metalloproteinases-2 and -9 play important roles in the development of breast cancer by hydrolyzing the extracellular matrix. Since −1306C/T and −1562C/T polymorphisms are located at the promoter regions of the matrix metalloproteinase-
Zahra Dehghan Manshadi, Mohammad Hamid, Farid Kosari, Heidar Tayebinia, Iraj Khodadadi   +4 more
doaj  

Expression of cellular adherent and invasive molecules in recurrent ovarian endometriosis

Journal of International Medical Research, 2020
Objective This study aimed to examine expression of cellular adhesion molecules and metalloproteinases of the extracellular matrix in ectopic endometrium for evaluating their roles in recurrence of endometriosis.
Tingting Wu, Rongyan Zhang, Qiaoying Jiang, Zhi Li, Ruijin Wu   +4 more
doaj   +1 more source

Matrix metalloproteinases-9 and tissue inhibitor of matrix metalloproteinases-1 in sarcoidosis patients [PDF]

Arhiv za farmaciju, 2017
Matrix metaloproteinases (MMPs) and their specific inhibitors - tissue inhibitors of matrix metalloproteinases (TIMPs) play an important role in pulmonary extracellular matrix destruction. Sarcoidosis is an inflammatory disease affecting multiple organs.
Ivanišević Jasmina, Stefanović Aleksandra, Kotur-Stevuljević Jelena, Jelić-Ivanović Zorana, Spasić Slavica, Videnović-Ivanov Jelica, Mihailović-Vučinić Violeta   +6 more
doaj   +1 more source

Human mast cells produce matrix metalloproteinase 9 [PDF]

European Journal of Immunology, 1999
Extracellular matrix-destructive enzymes, like matrix metalloproteinases (MMP), have been recognized in the process of inflammation and tissue remodeling and repair. The affected tissues often contain markedly increased numbers of mast cells. Although mast cells are capable of activating latent collagenase and proMMP, it has so far been unknown whether
N, Kanbe, A, Tanaka, M, Kanbe, A, Itakura, M, Kurosawa, H, Matsuda   +5 more
openaire   +2 more sources

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in recurrent chronic rhinosinusitis with nasal polyposis

Kaohsiung Journal of Medical Sciences, 2013
Matrix metalloproteinase (MMP) is involved in the upper airway remodeling process. We hypothesized that MMP had an additive effect on the formation of recurrent nasal polyp.
Ling-Feng Wang, Chen-Yu Chien, Feng-Yu Chiang, Chee-Yin Chai, Chih-Feng Tai   +4 more
doaj   +1 more source

Response of matrix metalloproteinase-9 to olfactory nerve injury [PDF]

NeuroReport, 2006
Matrix metalloproteinases function in the remodeling of the extracellular matrix during growth and development as well as in injury and disease processes. We examined the role of matrix metalloproteinase-9 in a model of olfactory nerve injury in mice. We measured changes in matrix metalloproteinase-9 protein levels for up to 60 days following olfactory
Richard M, Costanzo, Lisa A, Perrino, Masayoshi, Kobayashi   +2 more
openaire   +2 more sources

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Prognostic impact of matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase 9 (MMP-9) in Egyptian breast cancer patients

International Journal of Immunopathology and Pharmacology
This study aims to investigate the diagnostic and prognostic relevance of MMP-2 and MMP-9 as biomarkers for breast cancer, as well as their association with clinicopathological factors.
Fayrouz A Fouad, Mohamed A Khali, Inas Moaz, Hossam Elmasry, Nada Gheta, Asala Abdeen, Mariam Tantawi, Ganna Elkholy, Shaimaa Rihan, Mahmoud M Kamel, Ayman EL-Meghawry EL-Kenawy, Youssef AS Abdel-Moneim, Abdallah M Gameel   +12 more
doaj   +1 more source