Results 71 to 80 of about 233,826 (312)

Immunological targeting of matrix metalloproteinase-9 as a novel approach to universal cancer vaccine: characterization of anti-cancer antibodies efficacy in vitro [PDF]

, 2020
Objective: Therapeutic approach to cancer based on a vaccine targeting various types of cancer compared to being cancer-type specific has many advantages and can be applied to large population.
V. Ivanov, E. Efremov, A. Niedzwiecki, A. Goc, M. Rath, M. Chatterjee   +5 more
core   +1 more source

Expression of matrix metalloproteinases 9 and 12 in actinic cheilitis [PDF]

World Journal of Experimental Medicine, 2013
To investigate the role of matrix-degrading metalloproteinases 9, 12 (MMPs), as mediators of functional connective tissue damage in actinic cheilitis.Thirty five formalin-fixed, paraffin embedded specimens of actinic cheilitis, and twelve specimens of normal lower lip vermillion, which were obtained by the archives of the Department of Oral Medicine ...
Athanasios K, Poulopoulos, Dimitrios, Andreadis, Anastasios K, Markopoulos   +2 more
openaire   +2 more sources

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Induction of Matrix Metalloproteinase-9 in Keratinocytes by Histamine [PDF]

Journal of Investigative Dermatology, 2008
Mast cells and their mediator, histamine, are well-recognized effectors in immediate allergy, but their role in tissue remodeling and chronic inflammation has also been the focus of intense research during the past decade. Gschwandtner et al. (2008, this issue) report that histamine can induce MMP-9 expression in keratinocytes, promote collagen type IV
openaire   +2 more sources

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis–Associated Interstitial Lung Disease Risk

Arthritis Care &Research, EarlyView.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase‐7 (MMP‐7), and serum anti–malondialdehyde‐acetaldehyde (anti‐MAA) antibody for rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) risk stratification.
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

Levels of gingival crevicular metalloproteinases-8 and -9 in periodontitis

Saudi Dental Journal, 2010
Matrix metalloproteinases (MMPs), the key enzymes responsible for matrix degradation, are derived from polymorphonuclear leukocytes during the early stages of periodontitis.
Balwant Rai, Jasdeep Kaur, Rajnish Jain, Suresh C. Anand   +3 more
doaj   +1 more source

Environmental arsenic exposure and serum matrix metalloproteinase-9 [PDF]

Journal of Exposure Science & Environmental Epidemiology, 2012
The objective of this study was to evaluate the relationship between environmental arsenic exposure and serum matrix metalloproteinase (MMP)-9, a biomarker associated with cardiovascular disease and cancer. In a cross-sectional study of residents of Arizona, USA (n=215) and Sonora, Mexico (n=163), drinking water was assayed for total arsenic, and daily
Jefferey L, Burgess, Margaret, Kurzius-Spencer, Mary Kay, O'Rourke, Sally R, Littau, Jason, Roberge, Maria Mercedes, Meza-Montenegro, Luis Enrique, Gutiérrez-Millán, Robin B, Harris   +7 more
openaire   +2 more sources

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Role of Matrix Metalloproteinase 9 in Pituitary Tumor Behavior [PDF]

Journal of Clinical Endocrinology & Metabolism, 2000
The matrix metalloproteinases (MMPs) are a family of zinc-containing endopeptidases that are able to degrade the extracellular matrix and allow angiogenesis and tumor invasion. The vast majority of pituitary tumors are benign and do not metastasize to distant sites, although they may invade locally.
Turner, H, Nagy, Z, Esiri, M, Harris, A, Wass, J   +4 more
openaire   +3 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source