Results 121 to 130 of about 2,395,043 (357)

PECULIARITIES OF THE FIBROSIS AND CIRRHOSIS MONITORING AMONG CHILDREN WITH CHRONIC LIVER DISEASES

Педиатрическая фармакология, 2009
The researchers examined the opportunities to use determination in the serum among children with chronic liver diseases of various etiologies of the hyaluronic acid levels, collagen type IV, matrix metalloproteinase-2, tissue inhibitor of the matrix ...
A.N. Surkov, I.E. Smirnov, A.S. Potapov, A.G. Kucherenko, E.L. Tumanova   +4 more
doaj   +2 more sources

From Zn to Mn: the study of novel manganese-binding groups in the search for new drugs against tuberculosis. [PDF]

, 2011
In most eubacteria, apicomplexans, and most plants, including the causal agents for diseases such as malaria, leprosy, and tuberculosis, the methylerythritol phosphate pathway is the route for the biosynthesis of the C(5) precursors to the essential ...
de Oliveira, César Augusto F, McCammon, J Andrew, Vazquez, H, Williams, Sarah L   +3 more
core   +2 more sources

Microplastics from Wearable Bioelectronic Devices: Sources, Risks, and Sustainable Solutions

Advanced Functional Materials, EarlyView.
Bioelectronic devices (e.g., e‐skins) heavily rely on polymers that at the end of their life cycle will generate microplastics. For research, a holistic approach to viewing the full impact of such devices cannot be overlooked. The potential for devices as sources for microplastics is raised, with mitigation strategies surrounding polysaccharide and ...
Conor S. Boland
wiley   +1 more source

Eotaxin-induced expression of membrane type 1 matrix metalloproteinase mRNA in human eosinophils

Allergology International, 2000
Eosinophil penetration across the basement membrane (BM) is thought to be dependent on the degradation of membrane components. In this process, matrix metalloproteinases (MMP) appear to be primarily responsible for degradation of the BM.
Izumi Kurosaki, Taku Satoh, Koji Murakami, Takeshi Tastumi, Noriyasu Mitani, Ikuo Saiki   +5 more
doaj   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

Advanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia, Yajing Tian, Yunzhe Guo, Jiaying Li, Shengjie Cui, Cécile A. Dreiss, Eileen Gentleman, Xuedong Wang   +7 more
wiley   +1 more source

Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer

Journal of mammary gland biology and neoplasia, 2010
Matrix metalloproteinases (MMPs) degrade and modify the extracellular matrix (ECM) as well as cell-ECM and cell-cell contacts, facilitating detachment of epithelial cells from the surrounding tissue.
E. Radisky, D. Radisky
semanticscholar   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease. [PDF]

, 2006
BackgroundGlomerular basement membrane (GBM), a key component of the blood-filtration apparatus in the in the kidney, is formed through assembly of type IV collagen with laminins, nidogen, and sulfated proteoglycans.
Cosgrove, Dominic, Kalluri, Raghu, Khurana, Mona, Rao, Velidi H, Rougier, Jean-Philippe, Shield, Charles F, Werb, Zena, Werner, Michelle C, Zeisberg, Michael   +8 more
core   +3 more sources

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Genes for extracellular-matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development. [PDF]

, 1989
Christine Brenner, R. Adler, Daniel A. Rappolee, Roger A. Pedersen, Zena Werb   +4 more
openalex   +1 more source