Results 231 to 240 of about 157,261 (261)

Matrix degrading metalloproteinases

Journal of Neuro-Oncology, 1994
Matrix degrading metalloproteinases are enzymes that degrade proteins in tissue extracellular matrices. These proteinases exhibit specific, well defined properties that allow them to be classified into a family of enzymes. They are secreted by various cell types as the cells effect their surrounding extracellular matrix.
B W, Ennis, L M, Matrisian
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Matrix Metalloproteinases in Atherothrombosis

Progress in Cardiovascular Diseases, 2010
The metalloproteinases (MMPs, matrixins) are zinc-containing endopeptidases involved in the metabolism of extracellular matrix as well as in the cleavage of other proteins. The MMP family currently consists of 28 enzymes with somewhat different activities.
Magnus, Bäck, Daniel F J, Ketelhuth, Stefan, Agewall   +2 more
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Matrix Metalloproteinases and the Thyroid

Thyroid, 2000
Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade components of the extracellular matrix (ECM) and basement membrane. They play a critical role in many physiological and pathological processes, such as tumor metastasis. The original concept-that MMP activity during metastasis is restricted solely to invasion of the basement membrane
Z, Kraiem, S, Korem
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Matrix Metalloproteinases and Endometriosis

Seminars in Reproductive Medicine, 2003
Retrograde menstruation represents a plausible explanation for the development of most cases of endometriosis; nevertheless, additional factors must contribute to the development of disease in only 10 to 20% of women. The discriminating factor(s) in determining the development of active endometriosis probably involves a complex array of potentially ...
Kevin G, Osteen, Grant R, Yeaman, Kaylon L, Bruner-Tran   +2 more
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Matrix metalloproteinases and angiogenesis

Current Opinion in Nephrology and Hypertension, 2002
Angiogenesis is a prominent feature of numerous diseases, including cancer and arthritis, and appears to play an important role in kidney disease and hypertension. The matrix metalloproteinases, especially matrix metalloproteinase-2, play a vital role during angiogenesis by degrading the surrounding extracellular matrix and allowing endothelial cell ...
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Matrix metalloproteinases at a glance

Journal of Cell Science
ABSTRACT Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases that belong to the group of endopeptidases or matrixins. They are able to cleave a plethora of substrates, including components of the extracellular matrix and cell-surface-associated proteins, as well as intracellular targets. Accordingly, MMPs play key
Sven Hey, Stefan Linder
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Novel Matrix Metalloproteinase-9 (MMP-9) Inhibitors in Cancer Treatment

International Journal of Molecular Sciences, 2023
Sanaa Bardaweel
exaly  

Matrix Metalloproteinases

Advances in Dental Research, 1995
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A Role of Matrix Metalloproteinase-8 in Atherosclerosis

Circulation Research, 2009
CARLOS Lopez-Otin, Amrita Ahluwalia, Qingzhong Xiao   +2 more
exaly  

Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium

Fertility and Sterility, 2002
Ji Young Lee, Hye-Sung Moon, Mi Hye Park   +2 more
exaly