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Plasmin activates pro‐matrix metalloproteinase‐2 with a membrane‐type 1 matrix metalloproteinase‐dependent mechanism

Journal of Cellular Physiology, 2002
AbstractMembrane‐type 1 matrix metalloproteinase (MT1‐MMP) has been implicated as a physiological activator of progelatinase A (MMP‐2). We previously reported that plasmin treatment of cells results in proMMP‐2 activation and increased type IV collagen degradation. Here, we analyzed the role of MT1‐MMP in plasmin activation of MMP‐2 using HT‐1080 cells
Sara, Monea   +3 more
openaire   +2 more sources

Matrix metalloproteinase-1 and matrix metalloproteinase-9 are highly expressed in the joint capsule of diabetic frozen shoulder

Journal of Shoulder and Elbow Surgery
The pathophysiology of frozen shoulder (FS) involves abnormal expressions of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) that lead to capsular fibrosis. However, there has been little concern for why diabetic FS has more protracted fibrotic condition.
Du-Han Kim, Ji-An Kim, Chul-Hyun Cho
openaire   +3 more sources

Membrane-type matrix metalloproteinase 1

2004
Yoshifumi Itoh, Motoharu. Seiki
openaire   +1 more source

Matrix metalloproteinases in oral diseases (with accent on matrix metalloproteinase-1 in chronic periapical lesions)

2017
Matrix metalloproteinases (MMPs) are zinc and calcium dependent enzymes capable of degrading almost all extracellular matrix and basement membrane components. This group of proteolytic enzymes believed to be implicated in the breakdown of extracellular matrix in normal physiological processes, as well as, plays an important role in many destructive ...
Evrosimovska, Biljana, Dimova, Cena
openaire  

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