Results 221 to 230 of about 151,660 (260)

Investigation of Matrix Metalloproteinase -1, 2 and tissue inhibitor of matrix metalloproteinases-1 in Endometriosis

Journal of Nanjing Medical University, 2007
Objective: To explore the role of matrix metalloproteinase-1, 2 (MMP-1, MMP-2) and tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in endometriosis. Methods: The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.
Rong Liu, Demin Pu, Dan Yang
openaire   +1 more source

Role of matrix metalloproteinase-2, matrix metalloproteinase-9, and tissue inhibitors of metalloproteinase-1 in recurrent depression

The Scientific Journal of Al-Azhar Medical Faculty, Girls, 2020
Objectives Matrix metalloproteinases (MMPs) play a major role in inflammatory processes, and their effect in depression has been examined. This study evaluates MMP-2, MMP-9, and tissue inhibitors of metalloproteinase-1 (TIMP-1) in patients with major depressive disorder and in a control group of healthy individuals, as well as correlation between their
RaniaA Hamed, HebaA Elmalt, AbeerA.A Salama, SarahY Abozaid, ShaimaaY Abd Elaziz   +4 more
openaire   +1 more source

Matrix metalloproteinase-1 treatment of muscle fibrosis

Acta Biomaterialia, 2008
The onset of scarring after injury may impede the regeneration and functional recovery of skeletal muscle. Matrix metalloproteinase-1 (MMP-1) hydrolyzes type I collagen and thus may improve muscle regeneration by resolving fibrotic tissue. We examined the effect of recombinant human MMP-1 on fibrosis in the lacerated gastrocnemius muscle of NOD/scid ...
Joel L, Kaar, Yong, Li, Harry C, Blair, Gemma, Asche, Richard R, Koepsel, Johnny, Huard, Alan J, Russell   +6 more
openaire   +2 more sources

Matrix metalloproteinase-1 and skin ageing in smokers

The Lancet, 2001
Smokers look older than non-smokers of the same age. We have compared the concentrations of mRNA for matrix metalloproteinase 1 (MMP-1) in the buttock skin of smokers and non-smokers with quantitative real-time polymerase chain reactions. MMP-1 degrades collagen, which accounts for at least 70% of the dry weight of dermis.
Lahmann, C, Bergemann, J, Harrison, G, Young, A R   +3 more
openaire   +3 more sources

Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in perinatal asphyxia

Brain and Development, 2009
Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) play important roles in the function of the blood-brain-barrier (BBB). We investigated the roles of MMP-9 and TIMP-1 in the pathogenesis of hypoxic-ischemic encephalopathy following perinatal asphyxia.
Shinpei, Sunagawa, Takashi, Ichiyama, Rie, Honda, Shinnosuke, Fukunaga, Shinji, Maeba, Susumu, Furukawa   +5 more
openaire   +2 more sources

Matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 in vesicoureteral reflux

Pediatric Nephrology, 2011
The aim of this study was to investigate whether urine levels of matrix metalloproteinase 9 (uMMP9) and tissue inhibitor of metalloproteinase 1 (uTIMP1) are novel biomarkers of vesicoureteral reflux (VUR) and to determine the optimal cut-off levels of these enzymes to predict VUR in children.
Alev, Yilmaz, Ilmay, Bilge, Aysel, Kiyak, Asuman, Gedikbasi, Aysegul, Sucu, Bagdagul, Aksu, Sevinc, Emre, Aydan, Sirin   +7 more
openaire   +2 more sources

Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the outcome of coronary artery disease

Coronary Artery Disease, 2011
In this study, we investigated the association between matrix metalloproteinase-1 (MMP-1) G-1607GG, MMP-12 A-82G and MMP-12 A1082G genotypes and haplotypes and the prognosis of coronary artery disease (CAD).A total of 129 Tunisian patients with CAD were followed prospectively for a median of 2.5 years.
Imen, Jguirim-Souissi, Awatef, Jelassi, Afef, Slimani, Faouzi, Addad, Majed, Hassine, Khaldoun Ben, Hamda, Mohamed, Najah, Faouzi, Maatouk, Mustapha, Rouis, Mohamed Naceur, Slimane   +9 more
openaire   +2 more sources

Circulating matrix metalloproteinase-2 but not matrix metalloproteinase-3, matrix metalloproteinase-9, or tissue inhibitor of metalloproteinase-1 predicts outcome in patients with congestive heart failure

American Heart Journal, 2005
Extracellular matrix remodeling is thought to play an important role in the progression of heart failure (HF). Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are matrix-degrading enzymes that have been demonstrated to influence left ventricular properties and serve as targets of potential anti-remodeling agents ...
Jacob, George, Shuki, Patal, Dov, Wexler, Arie, Roth, David, Sheps, Gad, Keren   +5 more
openaire   +2 more sources

Differential Regulation of Stromelysin-1 (Matrix Metalloproteinase-3) and Matrilysin (Matrix Metalloproteinase-7) in Baboon Endometrium

Journal of the Society for Gynecologic Investigation, 2000
To investigate in vivo expression of matrix metalloproteinase enzymes (MMP), MMP-3 and MMP-7, by the baboon endometrium in relation to the process of tissue remodeling that accompanies menstruation in the primate.Endometrial tissues and uterine fluids obtained from reproductively intact cycling baboons, cycling baboons treated with an anti-progestin ...
K E, Cox, K L, Sharpe-Timms, N, Kamiya, M, Saraf, K M, Donnelly, A T, Fazleabas   +5 more
openaire   +2 more sources

Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the risk of ischemic stroke in a Tunisian population

Journal of the Neurological Sciences, 2014
Matrix metalloproteinases (MMPs) play an important role in early atherosclerosis, extracellular matrix remodeling, plaque rupture and myocardial infarction. MMP gene polymorphisms contribute to the risk of developing cardiovascular diseases. In this study, we investigated, for the first time, the association between MMP-1-16071G/2G, MMP-12 -82A/G and ...
Khouloud, Chehaibi, Mohamed Yahia, Hrira, Samir, Nouira, Faouzi, Maatouk, Khaldoun, Ben Hamda, Mohamed Naceur, Slimane   +5 more
openaire   +2 more sources