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ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu +9 more
wiley +1 more source
Proteomic signatures of equine dental tooth tissues in ageing and disease
Equine Veterinary Journal, EarlyView.Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen +8 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala +1 more
wiley +1 more source
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Coronary Artery Disease, 2011
Matrix metalloproteinases (MMPs), which are important regulators of extracellular matrix degradation, are known to induce atherosclerotic plaque rupture because of the degradation of collagen fibers in the fibrous cap. We aimed to investigate the possible association between these enzymes and objective coronary angiographic parameters of epicardial or ...
Elbeg, Sehri +3 more
openaire +3 more sources
Matrix metalloproteinases (MMPs), which are important regulators of extracellular matrix degradation, are known to induce atherosclerotic plaque rupture because of the degradation of collagen fibers in the fibrous cap. We aimed to investigate the possible association between these enzymes and objective coronary angiographic parameters of epicardial or ...
Elbeg, Sehri +3 more
openaire +3 more sources
Journal of Nanjing Medical University, 2007
Objective: To explore the role of matrix metalloproteinase-1, 2 (MMP-1, MMP-2) and tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in endometriosis. Methods: The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.
Rong Liu, Demin Pu, Dan Yang
openaire +1 more source
Objective: To explore the role of matrix metalloproteinase-1, 2 (MMP-1, MMP-2) and tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in endometriosis. Methods: The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.
Rong Liu, Demin Pu, Dan Yang
openaire +1 more source
Matrix metalloproteinase-1 treatment of muscle fibrosis
Acta Biomaterialia, 2008The onset of scarring after injury may impede the regeneration and functional recovery of skeletal muscle. Matrix metalloproteinase-1 (MMP-1) hydrolyzes type I collagen and thus may improve muscle regeneration by resolving fibrotic tissue. We examined the effect of recombinant human MMP-1 on fibrosis in the lacerated gastrocnemius muscle of NOD/scid ...
Joel L, Kaar +6 more
openaire +2 more sources
The Scientific Journal of Al-Azhar Medical Faculty, Girls, 2020
Objectives Matrix metalloproteinases (MMPs) play a major role in inflammatory processes, and their effect in depression has been examined. This study evaluates MMP-2, MMP-9, and tissue inhibitors of metalloproteinase-1 (TIMP-1) in patients with major depressive disorder and in a control group of healthy individuals, as well as correlation between their
RaniaA Hamed +4 more
openaire +1 more source
Objectives Matrix metalloproteinases (MMPs) play a major role in inflammatory processes, and their effect in depression has been examined. This study evaluates MMP-2, MMP-9, and tissue inhibitors of metalloproteinase-1 (TIMP-1) in patients with major depressive disorder and in a control group of healthy individuals, as well as correlation between their
RaniaA Hamed +4 more
openaire +1 more source
Matrix metalloproteinase-1 and skin ageing in smokers
The Lancet, 2001Smokers look older than non-smokers of the same age. We have compared the concentrations of mRNA for matrix metalloproteinase 1 (MMP-1) in the buttock skin of smokers and non-smokers with quantitative real-time polymerase chain reactions. MMP-1 degrades collagen, which accounts for at least 70% of the dry weight of dermis.
Lahmann, C +3 more
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Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in perinatal asphyxia
Brain and Development, 2009Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) play important roles in the function of the blood-brain-barrier (BBB). We investigated the roles of MMP-9 and TIMP-1 in the pathogenesis of hypoxic-ischemic encephalopathy following perinatal asphyxia.
Shinpei, Sunagawa +5 more
openaire +2 more sources