Results 201 to 210 of about 75,485,891 (288)

Fibroproliferative Remodeling of Immune‐Vascular Co‐Culture Spheroid Models in Response to Atherogenic Stimulation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Cell‐based models are highly valuable platforms for preclinical studies of atherosclerosis, offering controllable environments to investigate disease mechanisms. Three‐dimensional (3D) spheroids, a class of cell‐based models, enable the study of atherosclerotic disease phenomena under physiologically relevant yet controlled conditions. In this
Ibukunoluwa Naiyeju, Stephanie Lehoux, Maryam Tabrizian   +2 more
wiley   +1 more source

Regulation of matrix metalloproteinase-13 in cancer: Signaling pathways and non-coding RNAs in tumor progression and therapeutic targeting. [PDF]

World J Clin Oncol
Chidambaram D, Subashini V, Nanthanalaxmi M, Saranya I, Selvamurugan N.   +4 more
europepmc   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Unveiling Matrix Metalloproteinase 13's Dynamic Role in Breast Cancer: A Link to Physical Changes and Prognostic Modulation. [PDF]

Int J Mol Sci
Sun X, Hu X.
europepmc   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Correlation Between the Expression of Matrix Metalloproteinase-9, Matrix Metalloproteinase-13, Tissue Inhibitor of Metalloproteinases-1, p16 and Differentiation of Head and Neck Squamous Cell Carcinoma: A Prospective Observational Study. [PDF]

Ann Maxillofac Surg, 2021
Soni K, Elhence P, Kaushal D, Rajan N, Goyal A, Choudhury B, Sharma V.   +6 more
europepmc   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

MicroRNA‑4327 regulates TGF‑β1 stimulation of matrix metalloproteinase‑13 expression via CREB‑binding protein‑mediated Runx2 acetylation in human osteoblasts. [PDF]

Exp Ther Med
Kolipaka R, Magesh I, Karthik S, Ashok Bharathy MR, Saranya I, Preetha D, Selvamurugan N.   +6 more
europepmc   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

Spatial Mismatch Between Angiographic Obstruction and Plaque Destabilization in Acute Coronary Syndromes: A Conceptual Narrative Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The identification of the “culprit lesion” in acute coronary syndromes (ACS) traditionally relies on coronary angiography, assuming that the most severe stenosis, abrupt occlusion, or largest filling defect marks the site of plaque destabilization.
Fernando Quevedo‐Candela, Olivier F. Bertrand, Pedro Cepas‐Guillén, Jean‐Pierre Déry, David García‐Labbé, Andrés Ruhl, Eduardo Flores‐Umanzor, Tomas Cieza   +7 more
wiley   +1 more source