Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-13 [PDF]
Scientific Reports, 2023 Osteoarthritis (OA) is the most common joint disease associated with articular cartilage destruction. Matrix metalloproteinase-13 (MMP-13) has an essential role in OA pathogenesis by degradation of collagen II, a major component of articular cartilage ...
Aya Miyauchi +7 more
doaj +2 more sources
MMP-13, VEGF, and Disease Activity in a Cohort of Rheumatoid Arthritis Patients [PDF]
Diagnostics, 2023 Identifying certain serum biomarkers associated with the degree of rheumatoid arthritis (RA) activity can provide us with a more accurate view of the evolution, prognosis, and future quality of life for these patients. Our aim was to analyze the presence
Mihail Virgil Boldeanu +12 more
doaj +2 more sources
The Role of Matrix Metalloproteinases (MMP-8, MMP-9, MMP-13) in Periodontal and Peri-Implant Pathological Processes [PDF]
International Journal of Molecular Sciences, 2022 Mihai Covasa +2 more
exaly +2 more sources
Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis [PDF]
International Journal of Molecular Sciences, 2021 Melanie Ecker, Qichan Hu
exaly +2 more sources
Potential Value of Matrix Metalloproteinase-13 as a Biomarker for Osteoarthritis
Frontiers in Surgery, 2021 Background: Emerging knowledge has highlighted the role of matrix metalloproteinase (MMP)-13 in osteoarthritis (OA); however, the suitability of MMP-13 as a biomarker for OA remains unclear.
Xing Xin +16 more
doaj +1 more source
Disrupting mechanical homeostasis promotes matrix metalloproteinase-13 mediated processing of neuron glial antigen 2 in mandibular condylar cartilage [PDF]
European Cells & Materials, 2023 Post-traumatic osteoarthritis in the temporomandibular joint (TMJ OA) is associated dysfunctional cellmatrix mediated signalling resulting from changes in the pericellular microenvironment after injury.
M Bagheri Varzaneh +4 more
doaj +1 more source
Indole Inhibitors of MMP-13 for Arthritic Disorders [PDF]
ACS Omega, 2021 Steven J. Taylor +21 more
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Serum matrix metalloproteinase-13 as a diagnostic biomarker for cutaneous squamous cell carcinoma
BMC Cancer, 2021 Background A significant proportion of newly diagnosed patients with cutaneous squamous cell carcinoma (cSCC) have metastasis and eventually die of the disease, necessitating the exploration of novel biomarkers for early detection of cSCC aggressiveness,
Hui Wang +6 more
doaj +1 more source
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway
Bone & Joint Research, 2021 Aims: Interleukin (IL)-1β is one of the major pathogenic regulators during the pathological development of intervertebral disc degeneration (IDD). However, effective treatment options for IDD are limited.
Zi-Miao Liu +6 more
doaj +1 more source
The effects of morus nigra on the alveolar bone loss in experimentally-induced periodontitis
European Oral Research, 2019 Purpose The aim of this study is to evalute the anti-inflammatory effects of morus migra on experimentally-induced periodontitis in rats. Materials and Methods Twenty-four Wistar-albino rats were randomly divided into three groups: control group (C, n=8),
Elif Erdem +7 more
doaj +3 more sources