Results 281 to 290 of about 700,477 (342)

Before Symptoms Begin: Immune Activation in Preclinical ALS

Annals of Neurology, EarlyView.
Adriano Chiò, Andrea Calvo
wiley   +1 more source

Association between elevated serum matrix metalloproteinase-2 and tumor necrosis factor-α, and clinical symptoms in male patients with treatment-resistant and chronic medicated schizophrenia. [PDF]

BMC Psychiatry
Yang H, Peng R, Yang M, Zhang J, Shi Z, Zhang X.   +5 more
europepmc   +1 more source

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Matrix Metalloproteinase 2 (MMP2)

2016
Matrix Metalloproteinases (MMPs) are a family of glycoprotein enzymes, which are zinc-dependent endoproteinases. These degradative enzymes digest the blood-vessel walls to allow endothelial cells to escape and migrate toward the site of the angiogenic stimuli. MMPs play a role in angiogenesis in many different ways; endothelial cell migration caused by
A. Salajegheh
openaire   +2 more sources

Matrix metalloproteinase-2

Annals of the New York Academy of Sciences, 2006
Abstract:  The pathogenesis of abdominal aortic aneurysm (AAAs) involves progressive cycles of proteolysis and inflammation, the product of proteolysis driving subsequent inflammation. Little is yet known about the initiating events. We review the specific literature examining the possibility that MMP‐2 may be the initial catalyst.
Matt, Thompson, Gillian, Cockerill
openaire   +3 more sources

Matrix Metalloproteinase-2 in Dentin Matrix Mineralization

Journal of Endodontics, 2001
In the serum-free culture medium of bovine odontoblasts we detected active gelatinolytic metalloproteinases, matrix metalloproteinase (MMP)-2 and MMP-9 (gelatinases A and B). The activity of MMP-2, in particular, appeared suddenly around day 21 in the culture, coinciding with the development of odontoblastic cell processes and the loss of alkaline ...
M, Satoyoshi, A, Kawata, T, Koizumi, K, Inoue, S, Itohara, T, Teranaka, Y, Mikuni-Takagaki   +6 more
openaire   +2 more sources

Matrix metalloproteinase‐2 regulates the expression of tissue inhibitor of matrix metalloproteinase‐2

Clinical and Experimental Pharmacology and Physiology, 2010
Summary1. Matrix metalloproteinases (MMP) are associated with the vascular remodelling seen in atherosclerosis and aneurysm. The activation and activity of MMP‐2 are regulated by the intrinsic tissue inhibitor of MMP‐2 (TIMP‐2). The aim of the present study was to examine whether, conversely, MMP‐2 can affect the gene and protein expression of TIMP‐2.2.
Kaoru, Kimura, Xian Wu, Cheng, Kae, Nakamura, Aiko, Inoue, Lina, Hu, Haizhen, Song, Kenji, Okumura, Akihisa, Iguchi, Toyoaki, Murohara, Masafumi, Kuzuya   +9 more
openaire   +2 more sources

Matrix Metalloproteinase 2: Involvement in Keratoconus

European Journal of Ophthalmology, 2000
Purpose The activation of matrix metalloproteinase-2 (MMP-2) is postulated to be a crucial pathogenic factor behind progressive and chronic diseases in which basement membranes are disrupted. An ocular example is keratoconus. The purpose of the present enquiry was therefore to investigate and compare the activities of the MMP-2 secreted by keratocytes ...
V A, Smith, D L, Easty
openaire   +2 more sources

Matrix metalloproteinase-2 and matrix metalloproteinase-9 in mice with ocular toxocariasis

Parasitology Research, 2019
In ocular toxocariasis, Toxocara canis-induced inflammatory reaction can lead to eye destruction and granuloma, which is formed by immune cell infiltration and concurrent extensive remodeling tissue. Herein, the histomorphology of granuloma and proteinase production in the eye of T. canis-infected BALB/c mice were investigated.
Ling-Yuh Shyu, Ke-Min Chen, Shih-Chan Lai   +2 more
openaire   +2 more sources