Results 231 to 240 of about 140,703 (263)

Matrix Metalloproteinase-7 and Matrix Metalloproteinase-9 in Pediatric Multiple Sclerosis

Pediatric Neurology, 2012
Matrix metalloproteinases and their tissue inhibitors play a key role in the pathogenesis of adult-onset multiple sclerosis, and were suggested as biomarkers of response to interferon-β, an established treatment in multiple sclerosis. However, data regarding pediatric population are scarce.
Ünsal, Yılmaz, Yılmaz, Unsal, Kıvılcım, Gücüyener, Gücüyener, Kıvılcım, Ayşegül, Atak, Atak, Ayşegül, Arzu, Aral, Aral, Arzu, Esra, Gürkaş, Gürkaş, Esra, Ercan, Demir, Demir, Ercan, Ayşe, Serdaroğlu, Serdaroğlu, Ayşe   +13 more
openaire   +3 more sources

Matrix Metalloproteinase-9 in Lung Remodeling

American Journal of Respiratory Cell and Molecular Biology, 2003
Abstract Matrix metalloproteinase (MMP)-9 (Gelatinase B, 92-kD type IV collagenase, EC 3.4.24.35) is an MMP that is present in low quantities in the healthy adult lung, but much more abundant in several lung diseases, including asthma, idiopathic pulmonary fibrosis (IPF), and chronic obstructive pulmonary disease (COPD).
Jeffrey J, Atkinson, Robert M, Senior
openaire   +2 more sources

Matrix Metalloproteinase-9 in Cerebral Aneurysms

Neurosurgery, 1997
Generalized disruption of arterial wall morphological changes in patients harboring cerebral aneurysms has been documented; however, little is known regarding the pathogenesis of these changes. To explore the role of the elastolytic gelatinase, matrix metalloproteinase-9 (MMP-9), levels of this enzyme in the wall of intracranial aneurysms were compared
S C, Kim, M, Singh, J, Huang, C J, Prestigiacomo, C J, Winfree, R A, Solomon, E S, Connolly   +6 more
openaire   +2 more sources

Matrix Metalloproteinase-9 and Autoimmune Diseases

Journal of Clinical Immunology, 2006
Matrix metalloproteinases (also named matrixin or MMPs) are a major group of enzymes that regulate cell-matrix composition by using zinc for their proteolytic activities. They are essential for various normal biological processes such as embryonic development, morphogenesis, reproduction tissue resorption, and remodeling. Metalloproteinases also play a
Maya, Ram, Yaniv, Sherer, Yehuda, Shoenfeld   +2 more
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The role of matrix metalloproteinase-9 in dementia

Neuroscience Letters, 2003
Neurofibrillary tangles and senile plaques, constituted of extracellular amyloid deposits (Abeta), are the two defining pathological hallmarks of Alzheimer's disease (AD). Inhibiting the synthesis or aggregation of Abeta or increasing its clearance may reduce the detrimental effects of this peptide and consequently improve cognitive functions in ...
Nicole, Helbecque, Xavier, Hermant, Dominique, Cottel, Philippe, Amouyel   +3 more
openaire   +2 more sources

“Uncorking” of liposomes by matrix metalloproteinase-9

Chem. Commun., 2005
A triggered release methodology of liposomal contents via the enzyme MMP-9 is described.
Nihar R, Sarkar, Theresa, Rosendahl, Aaron B, Krueger, Abir L, Banerjee, Keith, Benton, Sanku, Mallik, D K, Srivastava   +6 more
openaire   +2 more sources

Comment on “Matrix Metalloproteinase-7 and Matrix Metalloproteinase-9 in Pediatric Multiple Sclerosis”

Pediatric Neurology, 2013
To the Editor: We read with interest the article by Unsal et al [1] indicating the levels of matrix metalloproteinasee9 (MMP-9), matrix metalloproteinase-7, and tissue inhibitor of metalloproteinase-1 (TIMP-1) in serum samples of children afflicted with multiple sclerosis (MS).
Hamid, Zahednasab, Mohammad, Balood, Seyed Alireza, Mesbah-Namin   +2 more
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Matrix metalloproteinase-9 and matrix metalloproteinase-2 gene polymorphisms in multiple sclerosis

Journal of Neuroimmunology, 2008
We investigated the association of matrix metalloproteinase-9 (-1562C/T, +279R/Q) and matrix metalloproteinase-2 (-1575G/A, -1306C/T) gene polymorphisms with multiple sclerosis (MS) susceptibility, gender differences and disability in 244 patients and 132 healthy subjects.
Yvonne, Benesová, Anna, Vasků, Pavel, Stourac, Magdalena, Hladíková, Michal, Beránek, Zdenek, Kadanka, Hana, Novotná, Josef, Bednarík   +7 more
openaire   +2 more sources

Matrix metalloproteinase-2 and Matrix metalloproteinase-9 in cholesteatoma and deep meatal skin

Clinical Otolaryngology and Allied Sciences, 1998
A qualitative and quantitative study of the presence of Matrix metalloproteinase-2 (MMP-2) and Matrix metalloproteinase-9 (MMP-9) in cholesteatoma was performed. Ten cholesteatoma and four deep meatal skin specimens were analysed for gelatinase activity at molecular weights corresponding to MMP-2 and MMP-9 using Sodium Dodecyl Sulphate Polyacrylamide ...
A R, Banerjee, R, James, A A, Narula
openaire   +2 more sources

Matrix metalloproteinase-9 and osteoporosis

2023
Introduction: Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteolytic enzymes involved in the degradation of extracellular matrix (ECM) components. The overexpression and increased activity of MMPs is observed in many physiological and pathological processes, including estrogen deficiency osteoporosis.
Grigoryan, Armine V., Betova, Tatyana M., Dimitrova, Anelia A., Kostov, Krasimir G., Blazhev, Alexander B.   +4 more
openaire   +1 more source